Results 51 to 60 of about 1,500,985 (317)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Low Utilization of Health Care Services following Screening for Hypertension in Dar es Salaam (Tanzania): A Prospective Population-based Study. [PDF]

, 2008
Drug therapy in high-risk individuals has been advocated as an important strategy to reduce cardiovascular disease in low income countries. We determined, in a low-income urban population, the proportion of persons who utilized health services after ...
Mkamba Mashombo, Pascal Bovet, Lengeler, Christian, Balampama Marianna, Bovet Pascal, Mashombo Mkamba, Balampama, M., Paccaud, Fred, Jean-Pierre Gervasoni, Christian Lengeler, Paccaud, F., Marianna Balampama, Mkamba, M., Mkamba, Mashombo, Paccaud Fred, Lengeler Christian, Balampama, Marianna, Gervasoni Jean-Pierre, Fred Paccaud, Bovet, Pascal, Gervasoni, Jean-Pierre, Bovet, P., Gervasoni, J.P., Lengeler, C.   +23 more
core   +1 more source

Health impact of shift work and night duty on part-time studying nurses

Orapuh Journal
Introduction In the demanding field of nursing, professionals often find themselves navigating the challenges of shift work and night duty, primarily due to a persistent shortage of nursing staff.
Lorato G. Manyeneng
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Project Retrosight. Understanding the returns from cardiovascular and stroke research: Case Studies [PDF]

, 2011
Copyright @ 2011 RAND Europe. All rights reserved. The full text article is available via the link below.This project explores the impacts arising from cardiovascular and stroke research funded 15-20 years ago and attempts to draw out aspects of the ...
Pollitt, A, Wooding, S, Hanney, S, Grant, J, Buxton, MJ   +4 more
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Associations between cardiovascular health and low thyroid function among US adults: a population-based study

Frontiers in Endocrinology
BackgroundHigher thyroid-stimulating hormone (TSH) amidst normal thyroid hormone (TH) levels may contribute to a negative impact on cardiovascular health (CVH).
Xiaoxiao Fang, Xiaoxiao Fang, Rui Hu, Shani Fei, Zhiguo Ding, Jiuli Zhao, Jianwei Shang   +6 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

‘It’s got to be another approach’: an Aboriginal Health Worker perspective on cardiovascular risk screening and education [PDF]

, 2014
This study provides a new perspective from Aboriginal Health Workers (AHWs) working in the area of heart health in the Aboriginal community of western Sydney.
Jennifer Reath, Tejas Deshmukh, Penelope Abbott   +2 more
core  

Construction of an odds model of coronary heart disease using published information: the Cardiovascular Health Improvement Model (CHIME)

, 2008
Background: There is a need for a new cardiovascular disease model that includes a wider range of relevant risk factors, in particular lifestyle factors, to aid targeting of interventions and improve population models of the impact of cardiovascular ...
Henry WW Potts, Martin, C.J., Potts Henry WW, Martin Christopher J, Paul Taylor, Christopher J Martin, Potts, H.W.W., Taylor, P., Taylor Paul   +8 more
core   +1 more source