Results 101 to 110 of about 549,307 (260)
Bosentan Reduces Myocardial Ischemia-Reperfusion Injury in Rats
Objectives: This study aimed to investigate the cardioprotective effects of bosentan, an endothelin receptor antagonist, against myocardial ischemia-reperfusion injury (MIRI) in rats.
Zeynep Yığman +6 more
doaj +1 more source
FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li +16 more
wiley +1 more source
Experimental cardiovascular surgery
A T, ANDREASEN, F, WATSON
openaire +2 more sources
Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao +28 more
wiley +1 more source
Cardiovascular diseases are the leading cause of mortality and disease burden among the elderly, both in China and globally. This underscores the importance of cultivating medical professionals with a deep understanding of the unique characteristics of ...
Zhu Cuilin +8 more
doaj +1 more source
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu +5 more
wiley +1 more source
Advances in postoperative autologous blood transfusion in cardiovascular surgery
Significant hemorrhage following cardiovascular surgery is common, with allogeneic blood transfusion frequently used, despite its association with increased complications and mortality.
SHAN Jiachen, JI Hongwen
doaj +1 more source
Cardiovascular surgery, as a specialized field of medicine, encompasses a wide range of interventions aimed at correcting structural and functional abnormalities of the heart and major vessels, based on an evolving understanding of pathophysiology, biomechanics, and regenerative biology. The article reviews historical milestones, contemporary minimally
Bozhyan, Sergey, Mallakhojaev, Anvarkhon
openaire +2 more sources
An implantable hydrogel is designed to enable in situ and on‐demand secretion of GLP‐1 in synovium through blue light irradiation to activate GLP‐1R/HK2/VDAC1 pathway for upregulating tricarboxylic acid cycle and oxidative phosphorylation in macrophage, facilitating tissue repair and bone erosion recovery.
Dahai Hu +10 more
wiley +1 more source
Objective To identify risk factors for postoperative respiratory failure (PORF) in cardiovascular surgery patients using machine learning algorithms and to construct a specific risk prediction model.
ZHOU Fuchao, LIU Xiang, LU Kaizhi
doaj +1 more source

