Results 181 to 190 of about 1,681,771 (209)

Semaphorin 3E‐Plexin‐D1 Pathway Downstream of the Luteinizing Hormone Surge Regulates Ovulation, Granulosa Cell Luteinization, and Ovarian Angiogenesis in Mice

Advanced Science, EarlyView.
The Semaphorin 3E (Sema3E)‐Plexin‐D1 pathway mediated by C/EBPα and C/EBPβ downstream of the luteinizing hormone (LH) surge plays important roles in the mouse preovulatory ovary. Timely activation and suppression of this pathway during the preovulatory stage are crucial for ovulation, corpus luteum formation, and proper angiogenesis.
Hanxue Zhang, Jimmy Dhillon, Paul D. Soloway, Bo Shui, Seoyeon Lee, Jennifer K. Grenier, Paul R. Munn, M. Cecilia Ljungberg, Rebecca B Williams, Rainer B. Lanz, Yu‐Hsiang Liao, Yi A. Ren   +11 more
wiley   +1 more source

Recent Advances in mRNA Delivery Systems for Cancer Therapy

Advanced Science, EarlyView.
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang, Ya‐Nan Fan, Si‐Qi Jiang, Ya‐Jing Ma, Yao‐Ru Yu, Yu‐Xin Qing, Qian‐Ru Li, Yi‐Lin Liu, Song Shen, Jun Wang   +9 more
wiley   +1 more source

Citrus reticulata Olive Oil: Production and Nutraceutical Effects on the Cardiovascular System in an In Vivo Rat Model of Metabolic Disorder. [PDF]

Nutrients
Spezzini J, Ciccone V, Macaluso M, Pieracci Y, Flamini G, Donnini S, Calderone V, Testai L, Zinnai A.   +8 more
europepmc   +1 more source

LRRC4 Deficiency Drives Premature Ovarian Insufficiency by Disrupting Metabolic Homeostasis in Granulosa Cells

Advanced Science, EarlyView.
LRRC4 deficiency disrupts the metabolic homeostasis of mitochondrial aerobic respiration and glycolysis during GC differentiation by inhibiting the ubiquitination‐mediated degradation of YAP, which ultimately leads to POI. These findings reveal the novel molecular etiology of POI and provide a promising target for prevention and treatment.
Yujie Shang, Yunjun Li, Di Han, Kun Deng, Wei Gao, Minghua Wu   +5 more
wiley   +1 more source

Dynamic VAD simulations: Performing accurate simulations of ventricular assist devices in interaction with the cardiovascular system. [PDF]

Int J Artif Organs
Crone V, Hahne M, Knüppel F, Wurm FH, Torner B.   +4 more
europepmc   +1 more source

The clinical characteristics analysis of serum markers for the cardiovascular system in early-stage COVID-19 patients. [PDF]

Front Cardiovasc Med
Cao X, Xie YL, Yi JY, Liu ZL, Zhang DD, Yue YY, Li TN, Zhou CL, Mu H.   +8 more
europepmc   +1 more source

A hybrid neural ordinary differential equation model of the cardiovascular system. [PDF]

J R Soc Interface
Grigorian G, George SV, Lishak S, Shipley RJ, Arridge S.   +4 more
europepmc   +1 more source

Human exposure to aerosol from indoor gas stove cooking and the resulting cardiovascular system responses. [PDF]

Toxicol Rep
Naseri M, Sultanbekovna AA, Malekipirbazari M, Kenzhegaliyeva E, Buonanno G, Stabile L, Hopke PK, Cassee F, Crape B, Sabanov S, Zhumambayeva S, Ozturk F, Tadi MJ, Torkmahalleh MA, Shah D.   +14 more
europepmc   +1 more source

The Influence of Long COVID on the Cardiovascular System and Predictors of Long COVID in Females: Data from the Polish Long COVID Cardiovascular (PoLoCOV-CVD) Study. [PDF]

J Clin Med
Bielecka-Dabrowa A, Kapusta J, Sakowicz A, Banach M, Jankowski P, Chudzik M.   +5 more
europepmc   +1 more source