Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu +9 more
wiley +1 more source
Pulsatile Physiological Control of Blood Pump-Cardiovascular System Based on Feedforward Compensation. [PDF]
Bao Y, Jing T, Ru W, Zhou L.
europepmc +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Effects of Environmental Conditions on Athlete's Cardiovascular System. [PDF]
Segreti A +9 more
europepmc +1 more source
The Impact of Arsenic, Cadmium, Lead, Mercury, and Thallium Exposure on the Cardiovascular System and Oxidative Mechanisms in Children. [PDF]
Wróblewski M +3 more
europepmc +1 more source
The relationship between adult phenylketonuria and the cardiovascular system - insights into mechanisms and risks. [PDF]
Dos Santos Y +7 more
europepmc +1 more source
The Impacts of Vaping on the Cardiovascular System: A Systematic Review of Case Reports. [PDF]
Nagy S +7 more
europepmc +1 more source
Space Travel: The Radiation and Microgravity Effects on the Cardiovascular System. [PDF]
Mircea AA +5 more
europepmc +1 more source
Evolved changes in reflex control of the cardiovascular system in deer mice native to high altitude.
Wearing OH, McGuire JJ, Scott GR.
europepmc +1 more source
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This article, which forms part of the life science series, examines the cardiovascular system, focusing on the anatomy and physiology of the heart. The blood flow through the heart is described and the regulatory mechanisms of the heart are identified and discussed.
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