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Age and the cardiovascular system
Hospital Medicine, 1999Congestive heart failure is a common cause of morbidity and mortality in the elderly population. Important changes occur in the structure and function of the cardiovascular system with advancing age. An understanding of these changes is vital for optimum management of these patients.
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Glitazones and the cardiovascular system
Current Opinion in Endocrinology, Diabetes & Obesity, 2008To chart recent progress on molecular mechanisms of rosiglitazone and pioglitazone in the cardiovascular system.Several classes of oral antidiabetic drugs are available to treat type 2 diabetes, but glitazones offer the unique promise of insulin-sensitizing ability coupled with potential to reverse cardiovascular abnormalities associated with insulin ...
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AGING AND THE CARDIOVASCULAR SYSTEM
Journal of Autonomic Pharmacology, 1986What has preceeded has been largely a listing of contradictory data: what follows is an attempt to gleam a pattern from all of this. In general, responsiveness is either reduced or unchanged by aging; reduced responsiveness has been demonstrated most frequently for cardiac β‐adrenoreceptors, cardiac muscarinic receptors, vascular β‐adrenoreceptors and ...
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Aquaporins in Cardiovascular System
2017Recent studies have shown that some aquaporins (AQPs ), including AQP1, AQP4, AQP7 and AQP9, are expressed in endothelial cells, vascular smooth muscle cells and heart of cardiovascular system. These AQPs are involved in the cardiovascular function and in pathological process of related diseases, such as cerebral ischemia , congestion heart failure ...
Lu, Tie +3 more
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Arrestins in the Cardiovascular System
2013Of the four mammalian arrestins, only the β-arrestins (βarrs; Arrestin2 and -3) are expressed throughout the cardiovascular system, where they regulate, as either desensitizers/internalizers or signal transducers, several G-protein-coupled receptors (GPCRs) critical for cardiovascular homeostasis.
Anastasios, Lymperopoulos +1 more
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Epac and the cardiovascular system
Current Opinion in Pharmacology, 2007Exchange protein activated by cyclic AMP (Epac) -- a cyclic AMP-activated guanine nucleotide exchange factor for Ras-like GTPases -- has emerged as a novel mediator of pivotal processes in the cardiovascular system, including cellular calcium handling, hypertrophy, integrin-mediated cell adhesion, establishment of cell polarity, cell migration and ...
Martina, Schmidt +4 more
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Sleep and the Cardiovascular System
2013There is a close relationship between the cardiovascular and respiratory systems, and between these systems and sleep, leading in turn to peculiar cardiovascular and respiratory changes during the sleep-wake cycle. Physiological changes during sleep may be disrupted in several pathological conditions, where cardiovascular and sleep alterations can be ...
Parati, G, Lombardi, C, Mancia, G
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Vanadate and cardiovascular system.
Giornale italiano di medicina del lavoro, 1995Rats were given 1, 10, 40, or 100 ppm of vanadium in drinking water for seven months, while rabbits received 1 ppm of vanadium (as sodium metavanadate, NaVO3) in drinking water for twelve months. Rats developed arterial hypertension through complex effects of vanadium on central neurogenic pathways, central and periferal catecholaminergic mechanisms ...
CARMIGNANI, Marco +4 more
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Mechanobiology of the cardiovascular system
Progress in Biophysics and Molecular Biology, 2021Zgierski-Johnston, Callum Micael +1 more
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Lysophospholipids and the cardiovascular system
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002The lysophospholipids sphingosine-1-phosphate (S1P) and lysophosphatidic acid (LPA) have varied effects on the cardiovascular system. S1P is necessary for normal vascular development and may play an important role in angiogenesis. These molecules may exert potentially detrimental effects.
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