Results 81 to 90 of about 20,284 (216)
Immunity, Inflammation and Disease, Volume 13, Issue 7, July 2025.Group A streptococcal M protein elicit antibody and T‐cell responses that cross react with cardiac and connective tissue proteins in the Rat Autoimmune Valvulitis (RAV) model of rheumatic heart disease. Bordetella pertussis Toxin induce a robust Th1 response that potentiates the autoimmune process in the RAV model A robust Th1/Th17 response was found ...
Rukshan A. M. Rafeek +6 more
wiley +1 more source
Preventive measures for Acute Rheumatic Fever/ Rheumatic Heart Disease : A literature review [PDF]
, 2013 Acute rheumatic disease is a major burden in the developing countries and also a major cause of premature death in children and young adults every year.
Kunwar, Nabina, Shrestha, Usha
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Animal Models and Experimental Medicine, Volume 8, Issue 6, Page 1138-1145, June 2025.Sydenham's chorea (SC) is the neurological manifestation associated with acute rheumatic fever (ARF), triggered by a group A streptococcal (GAS) infection. Anti‐GAS antibodies cross‐reacting with tissue proteins are implicated in the development of neurological changes. In this study, using an animal model, we demonstrate that a compromised blood–brain
Rukshan Ahamed Mohamed Rafeek +8 more
wiley +1 more source
Brain Aging in Patients With Cardiovascular Disease From the UK Biobank
Human Brain Mapping, Volume 46, Issue 8, June 1, 2025.This study reveals that in patients with certain cardiovascular diseases there is atypical biological brain age predicted by an artificial intelligence model from T1‐weighted brain MRIs. This suggests the existence of distinct aging‐like patterns within the brain in the precense of cardiovascular conditions.
Elizabeth Mcavoy +4 more
wiley +1 more source
Risk of carditis among adolescents after extending the interdose intervals of BNT162b2
npj VaccinesPrevious studies indicate an increased carditis risk among adolescents following the two-dose messenger RNA COVID-19 vaccine. Several jurisdictions have extended the interdose interval between the first and second doses to reduce the risk.
Min Fan +9 more
doaj +1 more source
Induction of Myocarditis and Valvuluitis in Lewis Rats by Different Epitopes of Cardiac Myosin and its Implications in Rheumatic Carditis [PDF]
, 2002 Immune responses against cardiac myosin and group A streptococcal M protein have been implicated in the pathogenesis of rheumatic heart disease.
Cunningham, Madeleine W. +5 more
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Cardiovascular magnetic resonance risk stratification in patients with clinically suspected myocarditis [PDF]
, 2014 BACKGROUND: The diagnosis of myocarditis is challenging due to its varying clinical presentation. Since myocarditis can be associated with significant 5-year mortality, and postmortem data show myocarditis in almost 10% of all adults suffering sudden ...
Anja Wagner +11 more
core +1 more source
Journal of Fish Diseases, Volume 48, Issue 5, May 2025.ABSTRACT Piscine orthoreovirus‐1 and 3 (PRV‐1, PRV‐3) cause highly prevalent infection in cultured salmonids and can induce heart and skeletal muscle inflammation (HSMI) resulting in economic losses in aquaculture. However, to date, PRV‐1 and PRV‐3 have withstood replication in continuous cell lines.
Torben Krebs +14 more
wiley +1 more source
Autoimmunity, 2019 Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are autoimmune mediated diseases triggered by group A streptococcal (GAS) infections. Molecular mimicry between GAS M-proteins and host tissue proteins has been proposed as the mechanism that ...
Suchandan Sikder +7 more
doaj +1 more source