Results 151 to 160 of about 14,283,857 (309)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Taking care of women entrepreneurs in deprived areas ? Supporting business in Politique de la ville

open access: yesGéoProximitéS
When women’s entrepreneurship is receiving political support from international to local scale, some associations are helping women to set up their own business in disadvantaged neighbourhoods. Entrepreneurship advisors seek to strengthen their capacity
Lorena Clément
doaj  

Challenges and Opportunities for Improving Care for Type 1 Diabetes in Older Adulthood. [PDF]

open access: yesDiabetes Care
Kahkoska AR   +10 more
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

La double invisibilisation du care réalisé par les femmes en situation de post-catastrophe climatique : l’exemple de la vallée de la Roya.

open access: yesGéoProximitéS
Following situations referred to as natural disaster (caused or not by humans), the concept of care (Tronto, 2008, 2012) is concrete because care activities become the main concern of everyone in order to ensure the vital needs of populations and of ...
Anouk Migeon
doaj  

Fall prevention for people with learning disabilities: key points and recommendations for practitioners and researchers [PDF]

open access: yes, 2018
National Institute for Health Care and Excellence (NICE)   +2 more
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Resident and Family Carer Perspectives on the Impact of Allied Health Student Placements on Service Delivery to Residents in Northern NSW Aged Care Homes: A Qualitative Study. [PDF]

open access: yesAust J Rural Health
Meares R   +11 more
europepmc   +1 more source

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