Results 151 to 160 of about 9,640,693 (303)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

A sustainable primary care approach for obesity

open access: yesThe Lancet Primary Care
The Lancet Primary Care
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

NURSING EDUCATION: WHERE HAVE WE BEEN; WHERE ARE WE GOING?*</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Revista Habanera de Ciencias Médicas</i>, 2007 </span><br><span class="r_sub"><i>W. Dean Care</i></span><br><small><a href="https://doaj.org/article/88af6a0232b543aa8a21b73564f95802" target="_blank" rel="nofollow" title="doaj.org/article/88af6a0232b543aa8a21b73564f95802">doaj</a> </small>   <br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1016/j.lanprc.2025.100097" target="_blank" rel="nofollow">Mental health care: from declarations to action</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>The Lancet Primary Care</i></span><br><span class="r_sub"><i> The Lancet Primary Care</i></span><br><small><a href="https://doaj.org/article/0dc2f6efe34c41f0b9680e2e5eb1d358" target="_blank" rel="nofollow" title="doaj.org/article/0dc2f6efe34c41f0b9680e2e5eb1d358">doaj</a> </small>   <div id="more_7" style="display:none"><a href="/sci_redir.php?doi=10.1016%2Fj.lanprc.2025.100097" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1016/j.lanprc.2025.100097'); alert('Copied the doi');">copy doi</a> <small>(10.1016/j.lanprc.2025.100097)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_7')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1111/scs.70329" target="_blank" rel="nofollow">How Nurses Assess Interventions to Promote Patients Sleep on Hospital Wards: Results of a Self-Report Survey.</a> <b><a href="https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC13696838&blobtype=pdf" target="_blank" rel="nofollow">[PDF]</a></b> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Scand J Caring Sci</i></span><br><span class="r_sub"><i>Vasse M<span id="ma_8" style="display:none">, Paala E, Kangasniemi M, Koivunen M.</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_8')">+3 more</a></small></i></span><br><small><a href="https://europepmc.org/article/MED/42928489#free-full-text" target="_blank" rel="nofollow" title="europepmc.org/article/MED/42928489#free-full-text">europepmc</a> </small>   <div id="more_8" style="display:none"><a href="/sci_redir.php?doi=10.1111%2Fscs.70329" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1111/scs.70329'); alert('Copied the doi');">copy doi</a> <small>(10.1111/scs.70329)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_8')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/1878-0261.70320" target="_blank" rel="nofollow">Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Molecular Oncology, EarlyView.</i></span><br><span class="r_content">Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...</span><br><span class="r_sub"><i>Lydia Xenou<span id="ma_9" style="display:none">, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_9')">+4 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/1878-0261.70320?mi=2or9o2m&af=R&AllField=care&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/1878-0261.70320?mi=2or9o2m&af=R&AllField=care&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small>   <div id="more_9" style="display:none"><a href="/sci_redir.php?doi=10.1002%2F1878-0261.70320" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/1878-0261.70320'); alert('Copied the doi');">copy doi</a> <small>(10.1002/1878-0261.70320)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_9')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1016/j.lanprc.2026.100138" target="_blank" rel="nofollow">PEN-Plus: a first step to better care</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>The Lancet Primary Care</i></span><br><span class="r_sub"><i> The Lancet Primary Care</i></span><br><small><a href="https://doaj.org/article/23a4834f1e974e7b899a87dc4a7436e1" target="_blank" rel="nofollow" title="doaj.org/article/23a4834f1e974e7b899a87dc4a7436e1">doaj</a> </small>   <div id="more_10" style="display:none"><a href="/sci_redir.php?doi=10.1016%2Fj.lanprc.2026.100138" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1016/j.lanprc.2026.100138'); alert('Copied the doi');">copy doi</a> <small>(10.1016/j.lanprc.2026.100138)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_10')">+1 more source</a></small><br></div><div class="r"><div style="margin-bottom:2px;overflow:hidden"><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-public_aspects_of_medicine/" class="suggestion"onclick="show_loader();"><b>public aspects of medicine</b></a><br/><a href="/q-medicine_general/" class="suggestion"onclick="show_loader();"><b>medicine general</b></a><br/><a href="/q-pharmacy_and_materia_medica/" class="suggestion"onclick="show_loader();"><b>pharmacy and materia medica</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"></div></div></div><div class="pagenav"><a href="/q-care/p-15/" rel="nofollow"><b>previous</b></a>   <a href="/q-care/p-14/" rel="nofollow">14</a>  <a href="/q-care/p-15/" rel="nofollow">15</a>  <b>16</b>  <a href="/q-care/p-17/" rel="nofollow">17</a>  <a href="/q-care/p-18/" rel="nofollow">18</a>   <a href="/q-care/p-17/" id="next" rel="nofollow"><b>next</b></a> </div><br></div> </div> <script>document.getElementById('loadingGif').style.display='none';</script><div style="width: 100%; height: 40px; bottom: 0px; background-color: #f5f5f5;"><div style="padding-left: 15px; padding-top: 10px"> <a href="/" rel="nofollow">Home</a> - <a href="/page-about/" rel="nofollow">About</a> - <a href="/page-disclaimer/" rel="nofollow">Disclaimer</a> - <a href="/page-privacy/" rel="nofollow">Privacy</a> </div></div> <link rel="stylesheet" href="//ajax.googleapis.com/ajax/libs/jqueryui/1.11.4/themes/smoothness/jquery-ui.min.css"/> <script> (function(ss,ex){ window.ldfdr=window.ldfdr||function(){(ldfdr._q=ldfdr._q||[]).push([].slice.call(arguments));}; (function(d,s){ fs=d.getElementsByTagName(s)[0]; function ce(src){ var cs=d.createElement(s); cs.src=src; cs.async=1; fs.parentNode.insertBefore(cs,fs); }; ce('https://sc.lfeeder.com/lftracker_v1_'+ss+(ex?'_'+ex:'')+'.js'); })(document,'script'); })('JMvZ8gvrWA9a2pOd'); </script> </body> </html>