Results 181 to 190 of about 9,640,693 (303)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

End-Of-Life Care in a Cardiac Intensive Care Unit: A Retrospective Analysis of Interventions During the Last 48 Hours. [PDF]

Nurs Crit Care
Gomes ET, Celes LB, Dos Reis Cirino GA.
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

A better future through primary health care

The Lancet Primary Care
The Lancet Primary Care
doaj   +1 more source

Quality Indicators in End-of-Life Care for Children With Cancer in Low- and Middle-Income Countries. [PDF]

Cancer Med
McNeil MJ, Quintero XG, Salek M, Agulnik A, Downing J, Dussel V, Friedrich P, Garcia WG, Johnston EE, Movsisyan N, Namisango E, Rao K, Sansom-Daly UM, Widger K, Wiener L, Rodriguez-Galindo C, Baker JN.   +16 more
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Misinformation, disinformation, and the fight for health

The Lancet Primary Care
The Lancet Primary Care
doaj   +1 more source

Collaboration for Healthy Ageing Through Preventive Home Visits: Identifying Home Visitors' Collaboration Partners. [PDF]

Scand J Caring Sci
Nivestam A, Westergren A, Haak M, Hedin G.   +3 more
europepmc   +1 more source

Other title: Long Term Care

application/pdfA set of 5 documents provided by the Office of the Kansas Long Term Care Ombudsman, with resources and information on Long Term Care.Kansas Office of the State Long-Term Care Ombudsman -- Kansas Office of the State Long-Term Care Ombudsman
Kansas. Long Term Care Ombudsman.
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source