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Results 201 to 210 of about 15,857,403 (360)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source

Inconsistencias conceptuales relacionadas con la utilización de los RNM

Pharmaceutical Care España, 2016
Fundación Pharmaceutical Care España -
doaj +2 more sources

The Correlation Between Stress of Conscience and Burnout Among Health Care Personnel at an Acute Care Hospital in Southern Sweden: A Cross-Sectional Study. [PDF]

Scand J Caring Sci
Ekstrand M, Ekwall A, Porter S.
europepmc +1 more source

Compassionate Care with Autonomous AI Humanoid Robots in Future Healthcare Delivery: A Multisensory Simulation of Next-Generation Models

Joannes Paulus Tolentino Hernandez
openalex +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source

NURSING EDUCATION: WHERE HAVE WE BEEN; WHERE ARE WE GOING?*</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Revista Habanera de Ciencias Médicas</i>, 2007 </span><br><span class="r_sub"><i>W. Dean Care</i></span><br><small><a href="https://doaj.org/article/88af6a0232b543aa8a21b73564f95802" target="_blank" rel="nofollow" title="doaj.org/article/88af6a0232b543aa8a21b73564f95802">doaj</a> </small> <br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1111/jorc.70046" target="_blank" rel="nofollow">Advance Care Planning Interventions for Adults With Chronic Kidney Disease: A Systematic Review.</a> <b><a href="https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC12833587&blobtype=pdf" target="_blank" rel="nofollow">[PDF]</a></b> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>J Ren Care</i></span><br><span class="r_sub"><i>Tiansaard J<span id="ma_7" style="display:none">, Bloomer MJ, Purtell L, Bonner A.</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_7')">+3 more</a></small></i></span><br><small><a href="https://europepmc.org/article/MED/41582599#free-full-text" target="_blank" rel="nofollow" title="europepmc.org/article/MED/41582599#free-full-text">europepmc</a> </small> <div id="more_7" style="display:none"><a href="/sci_redir.php?doi=10.1111%2Fjorc.70046" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1111/jorc.70046'); alert('Copied the doi');">copy doi</a> <small>(10.1111/jorc.70046)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_7')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.47276/lr.88.1.75" target="_blank" rel="nofollow">Knowledge, Attitudes and Practices relating to Leprosy among Public Health Care Providers in Colombo, Sri Lanka</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: diamond" title="open access: diamond" width="16" height="16">, 2017 </span><br><span class="r_sub"><i>Monika Priyadarshani Wijeratne<span id="ma_8" style="display:none">, Truls Østbye</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_8')">+1 more</a></small></i></span><br><small><a href="https://openalex.org/W3025798691" target="_blank" rel="nofollow" title="openalex.org/W3025798691">openalex</a> </small> <div id="more_8" style="display:none"><a href="/sci_redir.php?doi=10.47276%2Flr.88.1.75" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.47276/lr.88.1.75'); alert('Copied the doi');">copy doi</a> <small>(10.47276/lr.88.1.75)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_8')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/1878-0261.70152" target="_blank" rel="nofollow">Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Molecular Oncology, EarlyView.</i></span><br><span class="r_content">HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...</span><br><span class="r_sub"><i>Vanessa Tolotto<span id="ma_9" style="display:none">, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_9')">+13 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/1878-0261.70152?mi=2or9o2m&af=R&AllField=care&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/1878-0261.70152?mi=2or9o2m&af=R&AllField=care&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small> <div id="more_9" style="display:none"><a href="/sci_redir.php?doi=10.1002%2F1878-0261.70152" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/1878-0261.70152'); alert('Copied the doi');">copy doi</a> <small>(10.1002/1878-0261.70152)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_9')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/hpja.70144" target="_blank" rel="nofollow">Pacific Australia Labour Mobility Workers in Australia: Lived Experiences of Health and Navigating Health Systems.</a> <b><a href="https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC12820909&blobtype=pdf" target="_blank" rel="nofollow">[PDF]</a></b> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Health Promot J Austr</i></span><br><span class="r_sub"><i>Vaughan G, O'Mullan C, Preston R, Fox H.</i></span><br><small><a href="https://europepmc.org/article/MED/41562236#free-full-text" target="_blank" rel="nofollow" title="europepmc.org/article/MED/41562236#free-full-text">europepmc</a> </small> <div id="more_10" style="display:none"><a href="/sci_redir.php?doi=10.1002%2Fhpja.70144" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/hpja.70144'); alert('Copied the doi');">copy doi</a> <small>(10.1002/hpja.70144)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_10')">+1 more source</a></small><br></div><div class="r"><div style="margin-bottom:2px;overflow:hidden"><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-nursing/" class="suggestion"onclick="show_loader();"><b>nursing</b></a><br/><a href="/q-humans/" class="suggestion"onclick="show_loader();"><b>humans</b></a><br/><a href="/q-psychology/" class="suggestion"onclick="show_loader();"><b>psychology</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-internal_medicine/" class="suggestion"onclick="show_loader();"><b>internal medicine</b></a><br/><a href="/q-family_medicine/" class="suggestion"onclick="show_loader();"><b>family medicine</b></a><br/><a href="/q-intensive_care_medicine/" class="suggestion"onclick="show_loader();"><b>intensive care medicine</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-sociology/" class="suggestion"onclick="show_loader();"><b>sociology</b></a><br/><a href="/q-economics/" class="suggestion"onclick="show_loader();"><b>economics</b></a><br/><a href="/q-economic_growth/" class="suggestion"onclick="show_loader();"><b>economic growth</b></a><br/></div></div></div><div class="pagenav"><a href="/q-care/p-20/" rel="nofollow"><b>previous</b></a> <a href="/q-care/p-19/" rel="nofollow">19</a> <a href="/q-care/p-20/" rel="nofollow">20</a> <b>21</b> <a href="/q-care/p-22/" rel="nofollow">22</a> <a href="/q-care/p-23/" rel="nofollow">23</a> <a href="/q-care/p-22/" id="next" rel="nofollow"><b>next</b></a> </div><br></div> </div> <script>document.getElementById('loadingGif').style.display='none';</script><div style="width: 100%; height: 40px; bottom: 0px; background-color: #f5f5f5;"><div style="padding-left: 15px; padding-top: 10px"> <a href="/" rel="nofollow">Home</a> - <a href="/page-about/" rel="nofollow">About</a> - <a href="/page-disclaimer/" rel="nofollow">Disclaimer</a> - <a href="/page-privacy/" rel="nofollow">Privacy</a> </div></div> <link rel="stylesheet" href="//ajax.googleapis.com/ajax/libs/jqueryui/1.11.4/themes/smoothness/jquery-ui.min.css"/> </body> </html>