Results 41 to 50 of about 293,276 (262)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Has cross-level clinical coordination changed in the context of the pandemic? The case of the Catalan health system

BMC Health Services Research
Background The COVID-19 pandemic triggered numerous changes in health services organisation, whose effects on clinical coordination are unknown. The aim is to analyse changes in the experience and perception of cross-level clinical coordination and ...
Daniela Campaz-Landazabal, Ingrid Vargas, Elvira Sánchez, Francesc Cots, Pere Plaja, Joan Manuel Perez-Castejón, Antonio Sánchez-Hidalgo, María Luisa Vázquez   +7 more
doaj   +1 more source

Development of a specialty intensity score to estimate a patient's need for care coordination across physician specialties

Health Science Reports, 2021
Backgrounds and aims This article develops a Specialty Intensity Score, which uses patient diagnosis codes to estimate the number of specialist physicians a patient will need to access.
Ashley Hodgson, Thomas Bernardin, Benjamin Westermeyer, Ella Hagopian, Tyler Radtke, Ahmed Noman   +5 more
doaj   +1 more source

Lost in fragmentation — care coordination when somatic symptoms persist: a qualitative study of patients’ experiences [PDF]

, 2022
Hieke Barends, Femke Botman, Ella Walstock, Nikki Claassen-van Dessel, Johannes C. van der Wouden, Tim olde Hartman, Joost Dekker, Henriëtte E. van der Horst   +7 more
openalex   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

eHealth profile and care coordination of primary care physicians [PDF]

Eur J Public Health
Mathieu Jendly, Valérie Santschi, Stefano Tancredi, Arnaud Chioléro   +3 more
europepmc   +3 more sources

Improving the continuity and coordination of ambulatory care through feedback and facilitated dialogue—a study protocol for a cluster-randomised trial to evaluate the ACD study (Accountable Care in Germany) [PDF]

, 2021
Leonie Sundmacher, Ronja Flemming, Verena Leve, Isabel Geiger, Sebastian Franke, Thomas Czihal, Clemens Krause, Birgitt Wiese, Frank Meyer, Matthias Brittner, Johannes Pollmanns, Johannes Martin, Paul Brandenburg, Annemarie Schultz, Emmanuelle Brua, Udo Schneider, Olga Dortmann, Christoph Rupprecht, Stefan Wilm, Wiebke Schüttig   +19 more
openalex   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Care coordination between specialty care and primary care: a focus group study of provider perspectives on strong practices and improvement opportunities

Journal of Multidisciplinary Healthcare, 2015
Bo Kim,1,2 Michelle A Lucatorto,3 Kara Hawthorne,4 Janis Hersh,5 Raquel Myers,6 A Rani Elwy,1,7 Glenn D Graham81Center for Healthcare Organization and Implementation Research, Edith Nourse Rogers Memorial VA Hospital, Bedford, 2Department of Psychiatry ...
Kim B, Lucatorto MA, Hawthorne K, Hersh J, Myers R, Elwy AR, Graham GD   +6 more
doaj  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source