Results 81 to 90 of about 4,149,654 (191)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Scottish Journal of Residential Child CareA research study by Udayan Care (Beyond 18: Leaving Child Care Institutions-Supporting Youth Leaving Care, A Study of Aftercare Practices, 2019), in India, reveals that even though, as per the Juvenile laws of India, 'care-experienced' youth (care ...
Kiran Modi, Gurneet Kaur Kalra
doaj +1 more source
Trajectories of care leavers according to indicators of psychosocial adjustment: A cohort analysis
Child Protection and PracticeBackground: The study of the trajectories of care leavers regarding their involvement with a series of public services and institutions contributes to identify some indicators of psychosocial adjustment and therefor make proposals of improvement in their
Carme Montserrat, Joan Llosada-Gistau
doaj +1 more source
‘Who am I?’ How female care-leavers construct and make sense of their identity. [PDF]
, 2019 Identity formation may be more complex for those who have been in foster care in the face of childhood abuse, difficult relationships, unstable environments and multiple care contexts but this does not imply there is anything pathological about it. Given
Hassett, A., Colbridge, A.
core
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Pledge of Pride:A guide for supporting LGBTQ+ Care Leavers
, 2023 This resource has been produced as an output from the Leaving Care With Pride research project. The project aimed to address the dearth in knowledge exploring multiple intersecting disadvantages that UK lesbian, gay, bisexual, trans and queer (LGBTQ ...
Andrew, Charlotte +4 more
core +2 more sources
Exploring outcomes for children who have experienced out-of-home care in Western Australia.
International Journal of Population Data Science, 2018 Introduction Children who have been in out-of-home care have faced significant issues during their lives, and they are considered one of the most vulnerable groups in society.
Fernando Lima
doaj +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Social Work and Society, 2014 The purpose of this study is to examine young care leavers’ narrative accounts expressed as turning points connected to their experiences of being in care and leaving care. Telephone interviews were conducted with 65 young people, between 18 and 26 years
Ingrid Höjer, Yvonne Sjöblom
doaj +2 more sources