Results 111 to 120 of about 5,997,028 (302)

Understanding and classifying the raw water transfer invasion pathway [PDF]

open access: yes
Raw Water Transfer (RWT) schemes move large volumes of freshwater between separate waterbodies to supply water as a specific commodity. Water is translocated by complex purpose-built networks of pipelines, tunnels and water supply canals.
Waine, Ava   +2 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

The knowledge management on the elderly care

open access: yesInternational Journal of Integrated Care, 2009
Seija Arve   +4 more
doaj   +3 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Investigating health care pathways for anaphylaxis: Seeing the bigger picture through linked data

open access: yesJournal of Allergy and Clinical Immunology: Global
Background: Anaphylaxis is increasing in Australia involving all levels of the health care system. Although guidelines recommend calling an ambulance and 4-hour observation, knowledge gaps exist regarding where people experiencing anaphylaxis receive ...
Samantha L. Stiles, MPH   +7 more
doaj   +1 more source

Discussion Paper 4 [PDF]

open access: yes, 2016
It is widely understood that Family Carers are more likely to experience poor health (O’Sullivan, 2008), economic hardship (OECD, 2011), anxiety, stress, loneliness and isolation than the general population.
Care Alliance Ireland
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Sequential simulation (SqS) of a patient journey: an intervention to engage GP receptionists in integrated care

open access: yesInternational Journal of Integrated Care, 2015
Lis Paice   +4 more
doaj   +3 more sources

Improving the quality of patient care in lung cancer: key factors for successful multidisciplinary team working

open access: yesExploration of Targeted Anti-tumor Therapy
International Guidelines as well as Cancer Associations recommend a multidisciplinary approach to lung cancer care. A multidisciplinary team (MDT) can significantly improve treatment decision-making and patient coordination by putting different ...
Alessandro Morabito   +19 more
doaj   +1 more source

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