Results 71 to 80 of about 8,874,688 (352)
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Advance care planning in Parkinson’s disease: ethical challenges and future directions
npj Parkinson's Disease, 2019 Recent discoveries support the principle that palliative care may improve the quality of life of patients with Parkinson’s disease and those who care for them.
Leonard L. Sokol +13 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
What's Wrong With Advance Care Planning?
Journal of the American Medical Association (JAMA), 2021 R. Morrison, D. Meier, R. Arnold
semanticscholar +1 more source
Assessment of First-Year Use of Medicare's Advance Care Planning Billing Codes.
JAMA Internal Medicine, 2019 Assessment of First-Year Use of Medicare’s Advance Care Planning Billing Codes Advance care planning (ACP) conversations occur infrequently among patients and their health care professionals, and when they do occur, the context is often a stressful ...
K. Pelland +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Palliative Medicine, 2018 Background: Advance care planning is seen as an important strategy to improve end-of-life communication and the quality of life of patients and their relatives. However, the frequency of advance care planning conversations in practice remains low.
M. Zwakman +8 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source