Results 11 to 20 of about 6,847 (226)

The somatic care of patients with comorbid mental disorders: protocol of a mixed-methods study aiming to identify barriers to and enablers of utilization of somatic healthcare (SoKo) [PDF]

BMC Health Services Research, 2023
Background Healthcare for people with somatic and comorbid mental diseases can pose a challenge to the healthcare system. The aim of the SoKo study (the Somatic care of patients with mental Comorbidity) is to assess the current state of care and the ...
Sophie E. Groß, Isabell Schellartz, Jürgen Zielasek, Lara Schlomann, Inna Klee, Careen Ritschel, Sandra Engemann, Barbara Steffens, Michaela Jänner, Oliver Funken, Georg Juckel, Euphrosyne Gouzoulis-Mayfrank   +11 more
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Management of Uveitis Patients on Anti-TNF Agents Who Develop Demyelinating Disease – A Case Series [PDF]

Journal of Ophthalmic Inflammation and Infection
Background/Aims Anti-tumor necrosis factor (Anti-TNF) agents have proven beneficial for the treatment of chronic non-infectious uveitis, yet rare neurological complications and demyelinating disease can occur with their use.
Abel Hamdan, Sumit Sharma, Kimberly Baynes, Rula A. Hajj Ali, Careen Y. Lowder, Sunil K. Srivastava   +5 more
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Unveiling the Mechanisms of a Remission in Major Depressive Disorder (MDD)-like Syndrome: The Role of Hippocampal Palmitoyltransferase Expression and Stress Susceptibility [PDF]

Biomolecules
Post-translational modifications of proteins via palmitoylation, a thioester linkage of a 16-carbon fatty acid to a cysteine residue, reversibly increases their affinity for cholesterol-rich lipid rafts in membranes, changing their function.
Careen A. Schroeter, Anna Gorlova, Michael Sicker, Aleksei Umriukhin, Alisa Burova, Boris Shulgin, Sergey Morozov, Joao P. Costa-Nunes, Tatyana Strekalova   +8 more
doaj   +2 more sources

Neuro-Cells Mitigate Amyloid Plaque Formation and Behavioral Deficits in the APPswe/PS1dE9 Model of Alzheimer Disease While Also Reducing IL-6 Production in Human Monocytes [PDF]

Cells
Neuroinflammation is a key feature of Alzheimer’s disease (AD), and stem cell therapies have emerged as promising candidates due to their immunomodulatory properties.
Johannes de Munter, Kirill Chaprov, Ekkehard Lang, Kseniia Sitdikova, Erik Ch. Wolters, Evgeniy Svirin, Aliya Kassenova, Andrey Tsoy, Boris W. Kramer, Sholpan Askarova, Careen A. Schroeter, Daniel C. Anthony, Tatyana Strekalova   +12 more
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Differential Cytotoxic Effects of Cell-Free Supernatants of Emerging Pathogens Escherichia albertii and Escherichia fergusonii on Four Cell Lines Reveal Vero Cells as a Putative Candidate for Cytotoxicity Analysis [PDF]

Microorganisms
Escherichia albertii and Escherichia fergusonii are recognized as emerging pathogens with zoonotic potential. Despite their increasing importance, there is a paucity of data on the cytotoxicity of these two pathogens.
Kandhan Srinivas, Sandeep Ghatak, Kekungu-u Puro, Zakir Hussain, Mosuri Chendu Bharat Prasad, Arockiasamy Arun Prince Milton, Careen Liza Pakyntein, Dadimi Bhargavi, Samir Das, Madesh Angappan, Vanita Lyngdoh, Sabia Khan, Nur Abdul Kader, Umjerksiar Ramshon   +13 more
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Total Thrombus-Formation System in Patients with Peripheral Artery Disease [PDF]

Clinical and Applied Thrombosis/Hemostasis
The Total Thrombus-formation Analysis System (T-TAS) is an automated device using coated microchips to assess thrombus formation under flow conditions.
Christian Pfrepper MD, Careen Franke MD, Michael Metze MD, Maria Weise MD, Annelie Siegemund PhD, Roland Siegemund PhD, Martin Federbusch MD, Reinhard Henschler MD, Sirak Petros MD, Manuela Konert MD   +9 more
doaj   +2 more sources

A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types [PDF]

Nature Communications
Genome-wide spatial long-read approaches often lack single-cell resolution and yield limited read lengths. Here, we introduce spatial ISOform sequencing (Spl-ISO-Seq), which reveals exons and polyadenylation sites with near-single-cell resolution.
Careen Foord, Andrey D. Prjibelski, Wen Hu, Lieke Michielsen, Andrea Vandelli, Oleksandr Narykov, Brian Evans, Justine Hsu, Natan Belchikov, Julien Jarroux, Yi He, M. Elizabeth Ross, Iman Hajirasouliha, Gian Gaetano Tartaglia, Dmitry Korkin, Alexandru I. Tomescu, Hagen U. Tilgner   +16 more
doaj   +2 more sources

Increased Oxidative Stress in the Prefrontal Cortex as a Shared Feature of Depressive- and PTSD-Like Syndromes: Effects of a Standardized Herbal Antioxidant [PDF]

Frontiers in Nutrition, 2021
Major depression (MD) and posttraumatic stress disorder (PTSD) share common brain mechanisms and treatment strategies. Nowadays, the dramatically developing COVID-19 situation unavoidably results in stress, psychological trauma, and high incidence of MD ...
Johannes de Munter, Dmitrii Pavlov, Dmitrii Pavlov, Anna Gorlova, Anna Gorlova, Michael Sicker, Andrey Proshin, Allan V. Kalueff, Allan V. Kalueff, Allan V. Kalueff, Allan V. Kalueff, Andrey Svistunov, Daniel Kiselev, Daniel Kiselev, Daniel Kiselev, Andrey Nedorubov, Sergey Morozov, Aleksei Umriukhin, Klaus-Peter Lesch, Klaus-Peter Lesch, Klaus-Peter Lesch, Tatyana Strekalova, Tatyana Strekalova, Tatyana Strekalova, Tatyana Strekalova, Careen A. Schroeter   +25 more
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Ambivalence in Attitudes Toward Forgiveness

Interpersona: An International Journal on Personal Relationships, 2022
Are attitudes toward forgiveness ambivalent? To answer this question and explore whether such ambivalence predicts individuals’ propensity to forgive and tendency to view forgiveness as desirable/virtuous, we asked undergraduates (N = 159) to complete ...
Susan D. Boon, Megan Kheong, Careen Khoury   +2 more
doaj   +1 more source

Highlights of the ESC 2014 Conference

Journal of Community Engagement and Scholarship, 2022
Coverage of the 2014 Annual Conference of the Engagement Scholarship Consortium, featuring The keynote address from Dr. Rajesh Tandon Poster Session Award Winners First Place—Integrating High-Impact Scholarship into a General Education Class. By
Edward Mullins
doaj   +1 more source