Results 61 to 70 of about 382,232 (265)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Analysis of the Technical and Commercial Factors That Influence the Acquisition of Hybrid Vehicles in the City of Guayaquil

World Electric Vehicle Journal
Urban air pollution and emission reduction commitments have stimulated interest in cleaner vehicle technologies in Latin America, yet hybrid vehicle penetration in Ecuador, particularly in Guayaquil, remains limited.
Emerson Altamirano-Cañizares, Esneyder Bazurto-Murillo, Roberto López-Chila, Carlos Roche-Intriago   +3 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Mycobacterium Tuberculosis Infection: Participation of TH1, TH2, TH17 and Regulatory T Cells in the Immune Response

Acta Medica Iranica, 2018
Mycobacterium tuberculosis, the etiologic agent of Tuberculosis, is a pathogen that is widely distributed geographically. Tuberculosis is classified as a granulomatous inflammatory condition where effector cells accumulate at the site of mycobacterial ...
Gerardo Fernando Fernández Soto, Nereida Valero Cedeño, Carolina Arráiz de Fernández, Patricia Paredes Lascano, Miriam Fernández Nieto, María Teresa Peñaherrera Ron   +5 more
doaj  

Comparison of Cord Blood Lipid Profile among Appropriate for Gestational Age and Small for Gestational Age Term Neonates: A Cross-sectional Study

Indian Journal of Neonatal Medicine and Research
Introduction: Antenatal factors such as prematurity and Intrauterine Growth Restriction (IUGR) may influence the levels of various cord blood lipoproteins and subsequently predispose infants to early-onset ischaemic heart diseases.
Jasim Qureshi, Saman Beg, Jaigham Abbas, Ashish Verma, Akanksha Srivastava, Khatibur Rahman   +5 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

M-Shaped Conformal Antenna with FSS Backing for Gain Enhancement

Engineering Proceedings
A frequency selective surface (FSS) integrated conformal antenna is modelled and analytical study is presented in this article. A novel antenna design known as the “M-shaped Conformal Antenna with FSS Backing for Gain Improvement” makes use of both the ...
Madhavi Devi Lanka, Subbarao Chalasani
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Relationship between Serum Vitamin D Levels and HDL Cholesterol in Postmenopausal Women from Colombian Caribbean

Journal of Nutrition and Metabolism, 2018
Background. Previous evidence suggests that metabolic disorders in postmenopausal women could be related with low serum vitamin D levels. For example, vitamin D deficiency has been associated with increased risk factors for cardiovascular disease (CVD ...
Luz Adriana Sarmiento-Rubiano, José Armando Angarita Ruidiaz, Héctor Fernando Suarez Dávila, Alfonso Suarez Rodríguez, Roberto C. Rebolledo-Cobos, Jimmy E. Becerra   +5 more
doaj   +1 more source