Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec +5 more
wiley +1 more source
Elevating the allied health professions workforce: leadership's role in shaping professional identity. [PDF]
Hales P, Achour N, King O, Engward H.
europepmc +1 more source
xx xx. ABSTRACT Stimuli‐responsive nanomaterials capable of spatiotemporal control over drug release are of nanocomposite patch (“e‐Medi‐Patch”) engineered from biodegradable polycaprolactone (PCL), graphene nanoplatelets, and a redox‐active therapeutic, niclosamide. The hierarchical composite integrates π‐π interactions between aromatic drug molecules
Santosh K. Misra +7 more
wiley +1 more source
Modern societal changes and their impacts on students' identity: results in light of social cognitive theory. [PDF]
Alghamdi AA.
europepmc +1 more source
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez +4 more
wiley +1 more source
The influence of career calling on the work engagement of ideological and political theory teachers in colleges and universities: the chain mediating effect of organizational commitment and job satisfaction. [PDF]
Guo Y, Zhang M.
europepmc +1 more source
Nonlocal Conduction in a Metawire
A 1D metawire composed of twisted copper wires is designed and realized. This metamaterial exhibits pronounced effects of nonlocal electric conduction according to Ohm's law. The current at one location not only depends on the electric field at that location but also on other locations.
Julio Andrés Iglesias Martínez +3 more
wiley +1 more source
Value-added assessment of career planning for vocational competence based on deep learning. [PDF]
Zhang W.
europepmc +1 more source
Metal‐covalent organic frameworks (MCOFs) are novel porous materials that exhibit the advantages of covalent and metal‐organic frameworks. However, it is extremely difficult to resolve their atomic structure and better understand their structure‐properties relation. This work utilizes a synergistic combination of advanced microscopy, spectroscopic, and
Seán Hennessey +11 more
wiley +1 more source
Social media, digital literacy, and career competence: a mixed methods study among university students in China. [PDF]
Jian C, Zou D, Mahadi N.
europepmc +1 more source

