Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders
BOND‐PEP enables controllable, sequence‐first peptide binder design by grounding generation in binding evidence retrieved for each target. It uses topology‐conditioned message passing to integrate relevant peptide examples with the target protein sequence, forming a residue‐level representation that guides the generation of diverse, target‐specific ...
Wenze Ding
wiley +1 more source
Gender-based differences in work styles and career satisfaction in the retina subspecialty in Japan. [PDF]
Maruyama-Inoue M +4 more
europepmc +1 more source
Origami has inspired numerous soft deployable mechanisms for safe human‐robot interaction, while its intrinsic kinematic instability at arbitrary configurations limited their practical robotic application. This work presents a 3D printed meter‐scale origami robotic actuator capable of load‐bearing deformation through creaseline stiffness modulation.
Sung Yol Yu +5 more
wiley +1 more source
Associations of Nurses' Career Attitudes, Career Management Behaviors, and Understanding and Expected Outcomes of The Career Ladder System With Intention to Stay and Career Satisfaction: A Cross-Sectional Study. [PDF]
Kim AR +5 more
europepmc +1 more source
How Is Professional Identity Associated with Teacher Career Satisfaction? A Cross-Sectional Design to Test the Multiple Mediating Roles of Psychological Empowerment and Work Engagement. [PDF]
Sun B +5 more
europepmc +1 more source
IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis
The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui +12 more
wiley +1 more source
Exploring the determinants of career satisfaction among Pakistani dentists: a nationwide cross-sectional study. [PDF]
Yasin O +5 more
europepmc +1 more source
A universal hydrogel microparticle template with five DNA‐addressable domains decouples particle fabrication from barcode writing. Contact‐free multilaminar flow lithography produces >106 templates/h, and post‐fabrication domain‐selective hybridization converts one batch into large, user‐defined optical barcode libraries with robust decoding and re ...
Akihiro Eguchi +5 more
wiley +1 more source
Job stress, coping resources and teacher career satisfaction: a questionnaire survey based on China's "double reduction" policy. [PDF]
Ding B, Wang Y, Li F.
europepmc +1 more source
The predictive value of high school grade point average to academic achievement and career satisfaction of dental graduates. [PDF]
Al-Asmar AA +4 more
europepmc +1 more source

