Results 91 to 100 of about 132,276,789 (252)

The new statutory requirements in careers guidance in England and the implications for careers provision under the Coalition Government [PDF]

open access: yes, 2015
The Education Act 2011 passed responsibility for careers guidance in England from local authorities to schools, providing no extra funding or staff training.
Chadderton, C   +2 more
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

“Science Is Important, but Why?” Primary-Age Children’s Lack of Understanding of Why We Study STEM and the Nature of Science Careers

open access: yesSocial Sciences
Despite persistent concerns about STEM workforce shortages in the UK, efforts to promote science study and careers have had limited success in translating into aspirations among young people.
Cherry Canovan, Robert Walsh
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Science (without) youth: Gendering Early Academic Careers in Slovenia

open access: yesAS: Andragoška Spoznanja, 2018
How is it possible to foster gender equality in academia if the academic field is gradually marked by precarity, particularly in the early stages of academic careers?
Ana Hofman
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A professional development program with an assessed ePortfolio: A practical solution for engaging undergraduates with their career development in large student cohorts

open access: yesJournal of Teaching and Learning for Graduate Employability, 2019
Undergraduate biomedical science degree-programs are considered to be non-vocational, with a diverse range of career outcomes. At our university, student and academic feedback indicated that biomedical science students were anxious and uncertain about ...
Julia Choate   +4 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

eLife and early career researchers

open access: yeseLife, 2013
There are many reasons for submitting your best work to eLife, especially if you are an early career researcher.
Randy Schekman   +2 more
doaj   +1 more source

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