Results 121 to 130 of about 90,086 (258)

Tilting the balance toward motor symptoms: Determinants of caregiver burden in late-stage Parkinson's disease. [PDF]

IBRO Neurosci Rep
Culicetto L, Triolo G, Lombardo R, Ivaldi D, Bonanno L, Giambò FM, Di Lorenzo G, Sorbera C, Quartarone A, Marino S, Buono VL.   +10 more
europepmc   +1 more source

Limited Discrepancy Between Cognitive Ability and Daily Living Skills in Autism: A Longitudinal Study From Ages 2–25

Autism Research, EarlyView.
ABSTRACT Many autistic individuals with average or higher cognitive abilities (also referred to as intelligence quotient; IQ) exhibit weaker than expected daily living skills (DLS). However, existing evidence is primarily cross‐sectional. This study examined: (1) how IQ‐DLS discrepancies develop from early childhood through early adulthood, (2) whether
Elaine B. Clarke, Catherine Lord, Vanessa H. Bal   +2 more
wiley   +1 more source

Caregiver Burden, Social Support, and Depressive Symptoms Among Caregivers of Patients With Heart Failure. [PDF]

J Nurs Res
Kim DY, Choi J, Son YJ.
europepmc   +1 more source

The Effectiveness of Acceptance and Commitment Therapy Group Intervention (Navigator ACT) for Parents of Children With Neurodevelopmental Disabilities: A Randomized Controlled Trial

Autism Research, EarlyView.
ABSTRACT High levels of parental stress and psychological inflexibility are common among caregivers raising children with neurodevelopmental disabilities. Navigator ACT is a group‐based treatment developed to increase psychological flexibility and reduce the impact of stress among parents of children with various disabilities (e.g., autism spectrum ...
T. Holmberg Bergman, P. Lappalainen, A. Ghaderi, T. Hirvikoski   +3 more
wiley   +1 more source

Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults

Autism Research, EarlyView.
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin, Arthur N. Westover, Amy S. F. Lutz, Manish K. Jha   +3 more
wiley   +1 more source

Effectiveness of Souvenaid® combined with acetylcholinesterase inhibitors on caregiver burden in Alzheimer´s disease. [PDF]

Alzheimers Dement (N Y)
García-Alberca JM, Mendoza S, DE LA Guía P, López DE LA Rica M.   +3 more
europepmc   +1 more source

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

British Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić, Elvira Meni Maria Gkrinia, Patrick Eustaquio, Andrea Katrin Faour, Dinko Vitezić   +4 more
wiley   +1 more source

Caregiver Burden in Head and Neck Cancer: The Combined Impact of Clinical Complexity and Psychological Distress. [PDF]

J Clin Med
Duymaz YK, Bostanci SA, Cubuk H, Yigit Kocer YE, Oruc Akcay G, Sahin Yılmaz AA.   +5 more
europepmc   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

British Journal of Clinical Pharmacology, EarlyView.
Within the ConcePTION project we set out to design two mother–infant pair studies collecting breast milk and plasma from the mother and plasma from the infant (for metformin and prednisolone) in order to demonstrate the premises and conditions for investigating potential drug transfer in association with breastfeeding.
Mats Hansson, Ida Björkgren, Jenny Svedenkrans, Helena Backman, Jarl Hellman, Linda Englund‐Ögge, Mikaela Magnusson, Inger Lindström, Andrea Wutte, Erica Sundell, Pawel Baranczewski, Laura Shaughnessy   +11 more
wiley   +1 more source