Results 131 to 140 of about 90,086 (258)

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

British Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source

Factors linked to informal caregiver burden in dementia across Latin America and the Caribbean: A systematic review and meta-analysis. [PDF]

Alzheimers Dement
Quintero-Cardona P, Tangarife MA, Blandon J, Arango-Lasprilla JC, Ibanez A, Baez S.   +5 more
europepmc   +1 more source

Cost–benefit analysis of screening programme for diabetic retinopathy in Bulgaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Late‐diagnosed diabetic retinopathy (DR) is difficult and expensive to treat. Screening programmes can identify the disease early and reduce the costs of its future treatment. This study aims to analyse the cost–benefit of screening programmes for DR.
Iva Nenkova, Yoana Lilova, Alexander Oscar, Alina Levi, Maria Kamusheva, Guenka Petrova   +5 more
wiley   +1 more source

Stroke caregiving in Asia: A scoping review of caregiver burden. [PDF]

Dialogues Health
Yunding J, Saleh LM, Tahir T, Wahyu A, Sidin AI, Arsyad M, Yusuf S, Ngkolu NW.   +7 more
europepmc   +1 more source

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

British Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić, Ivana Stević, Elvira Meni Maria Gkrinia, Dinko Vitezić, Slobodan Janković   +4 more
wiley   +1 more source

Emotional and Caregiver Burden in Adults with Glaucoma-Related Blindness at a Chinese Tertiary Center. [PDF]

Clin Ophthalmol
Luo Z, Konatsu K, Yang Y, Cheng L, He Y, Zhang Y, Han Y, Huang J.   +7 more
europepmc   +1 more source

Self-Awareness in Survivors of an Acquired Brain Injury and Its Impact on Caregiver Burden. [PDF]

Brain Sci
Barcenas C, Klonoff P, Theodorou A, Van Doren J, Schaffer S, Koberstein E, Murthy J, Del Pino Luna M, Palmer Cancel S.   +8 more
europepmc   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Management of Informal Caregiver Burden in a Case of Primary Cerebral Ewing's Sarcoma: A Case Report. [PDF]

Int Med Case Rep J
Gambarin M, Picelli A, Varalta V, Santini B, Fontana L, Filippetti M, Smania N, Di Censo R.   +7 more
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source