Results 151 to 160 of about 90,976 (257)

Executive Functioning as a Pathway Between Social Skills and Psychopathology: The Moderating Role of Autism Diagnosis

Autism Research, EarlyView.
ABSTRACT Internalizing and externalizing problems are highly prevalent among children and adolescents, with higher rates observed particularly among those with neurodevelopmental disorders. Previous studies have identified deficits in social competence and executive functioning (EF) as predictive factors of internalizing and externalizing problems, and
Samina I. Ansari, Lucas A. Martin, Kristi C. Guest, Rajesh K. Kana   +3 more
wiley   +1 more source

Factors influencing the caregiver burden on primary family caregivers of stroke survivors: a scoping review. [PDF]

Qual Life Res
Hongwei Y, Juan W, Hui J, Zhongjian L, Xuechun L, Yaqiong A, Mingyue Z, Lingmei R, Xiaoqian W.   +8 more
europepmc   +1 more source

A Factor‐Analytic Approach for Psychometric Properties of the Repetitive Behaviors Questionnaire‐3 (RBQ‐3) for Turkish Population

Autism Research, EarlyView.
ABSTRACT Restricted and repetitive behaviors (RRBs) are one of the diagnostic criteria for autism spectrum disorders (ASD), as well as being found in the general population. The current study aims to explore the psychometric properties of the Turkish self‐report and informant‐report forms of the Repetitive Behaviors Questionnaire‐3 (RBQ‐3) for ...
Volkan Avşar, Hatice Şengül Erdem, Asiye Şengül Avşar   +2 more
wiley   +1 more source

Cortical Network Overconnectivity Relates to Sensory, Cognitive, and Social Dimensions in Young Children With Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT The heterogeneity in both the neurobiological mechanisms and the phenotypic presentations of autism spectrum disorder (ASD) poses a major challenge to clinical and translational research. Alterations in functional connectivity (FC) have been associated with ASD, yet it remains unclear whether and how divergent brain network properties may ...
Borja Rodríguez‐Herreros, Ahmad Mheich, Joana Maria Almeida Osório, Sonia Richetin, Vincent Junod, Lorène Arnold, Victoria Aeschbach, Lilia Nora Adamou, Katherina Gschwend, Laura Mendes, David Romascano, Paola Yu, Marine Jequier Gygax, Anne M. Maillard, Micah M. Murray, Mahmoud Hassan, Nadia Chabane   +16 more
wiley   +1 more source

Sleep in Young Children With Autism, ADHD and Combined Presentations

Autism Research, EarlyView.
ABSTRACT Autism and attention deficit hyperactivity disorder (ADHD) are often accompanied by sleep problems. Longitudinal studies hint towards a greater proportion of persisting sleep problems across early development in neurodivergent compared to neurotypical individuals. Within the context of a prospective infant sibling study of autism and ADHD (n = 
Eva‐Maria Kurz, Sven Bölte, Terje Falck‐Ytter   +2 more
wiley   +1 more source

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

British Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić, Elvira Meni Maria Gkrinia, Patrick Eustaquio, Andrea Katrin Faour, Dinko Vitezić   +4 more
wiley   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

British Journal of Clinical Pharmacology, EarlyView.
Within the ConcePTION project we set out to design two mother–infant pair studies collecting breast milk and plasma from the mother and plasma from the infant (for metformin and prednisolone) in order to demonstrate the premises and conditions for investigating potential drug transfer in association with breastfeeding.
Mats Hansson, Ida Björkgren, Jenny Svedenkrans, Helena Backman, Jarl Hellman, Linda Englund‐Ögge, Mikaela Magnusson, Inger Lindström, Andrea Wutte, Erica Sundell, Pawel Baranczewski, Laura Shaughnessy   +11 more
wiley   +1 more source

Multilevel influences on family caregiver burden in diabetic foot ulcer care: a qualitative study. [PDF]

BMC Nurs
Li Y, Zhuang H, Gao Y, Yan Q, Du L, Hu Y, Zhao Z, Lin R, Liang C, Xiao Y, Guan Z, Yu H.   +11 more
europepmc   +1 more source

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

British Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source