Results 71 to 80 of about 799,375 (314)

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

The needs of family members caring for people living with mental illness: An integrated review

Health SA Gesondheid: Journal of Interdisciplinary Health Sciences
Background: Family members caring for people living with mental illness (PLWMI) are prone to grapple with caregiver burden. The caregivers often contend with a decline in their mental and physical well-being while executing their role.
Keletwaetse Sakwape, Gaotswake P. Kovane, Precious C. Chukwuere, Miriam Moagi, Rorisang Machailo   +4 more
doaj   +1 more source

The Mediating Effects of Positive Cognitions on Autism Caregivers\u27 Depression and Their Children\u27s Challenging Behaviors [PDF]

, 2016
Caregivers of persons with Autism Spectrum Disorders (ASD) are prone to depression and psychological problems, which have an impact on their children\u27s challenging behaviors. Positive cognitions include specific positive thinking patterns that enhance
Bekhet, Abir K.
core   +1 more source

Non-parental caregivers, parents, and the school readiness of the children of Latino/a immigrants [PDF]

, 2017
School readiness generally predicts trajectories of academic achievement over time, motivating efforts to support the development of school readiness skills by expanding access to and improving the quality of early childhood care and education.
Pivnick, Lilla Kármán
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Advance directives of lung cancer patients and caregivers in China: A cross sectional survey

Thoracic Cancer, 2020
Background This study aimed to investigate lung cancer patients and attitudes of their caregivers toward advance directives (ADs) in China. Methods A cross sectional study was conducted in the Department of Oncology outpatient clinic in West China ...
Chenchen Feng, Juan Wu, Junying Li, Han Yu Deng, Jiewei Liu, Shuzhen Zhao   +5 more
doaj   +1 more source

The burden of epilepsy and unmet need in people with focal seizures

Brain and Behavior, 2022
Background Epilepsy is one of the most common neurological conditions worldwide. As a chronic condition, epilepsy imposes a significant burden on people with epilepsy and society.
Persefoni Ioannou, Daniella L. Foster, Josemir W. Sander, Sophie Dupont, Antonio Gil‐Nagel, Ewa Drogon O'Flaherty, Elena Alvarez‐Baron, Jasmina Medjedovic   +7 more
doaj   +1 more source

Technology and Caregiving: Emerging Interventions and Directions for Research. [PDF]

, 2020
An array of technology-based interventions has increasingly become available to support family caregivers, primarily focusing on health and well-being, social isolation, financial, and psychological support.
Apesoa-Varano, Ester Carolina, Gladstone, Caroline, Kim, Katherine K, Lindeman, David A   +3 more
core  

Children's Medicines in Tanzania: A National Survey of Administration Practices and Preferences. [PDF]

, 2013
The dearth of age-appropriate formulations of many medicines for children poses a major challenge to pediatric therapeutic practice, adherence, and health care delivery worldwide.
AN Sachs, Cameron T. Nutt, D Baguley, D Notterman, DC Knoppert, DM Taylor, E Ansah, Elia John Mmbaga, G Peacock, Gary J. Noel, H Zucker, Helga Naburi, Imti Choonara, J Breitkreutz, J Teng, JA Mennella, K Hoppu, K Hoppu, K Hoppu, Lisa V. Adams, M Gazarian, P Nahirya-Ntege, Rodrick Kisenge, S Beggs, S Hill, S MacLeod, Sienna R. Craig, SR Craig, SR Hill, Stephen P. Spielberg, T Nunn, Timothy Lahey, W Rodriguez   +32 more
core   +3 more sources