Results 71 to 80 of about 540,940 (260)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Family Caregivers, Patients and Physicians: Ethical Guidance to Optimize Relationships

, 2010
Family caregivers play a major role in maximizing the health and quality of life of more than 30 million individuals with acute and chronic illness.
Hood, Virginia L, Mitnick, Sheryl, Leffler, Cathy   +2 more
core   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

The needs of family members caring for people living with mental illness: An integrated review

Health SA Gesondheid: Journal of Interdisciplinary Health Sciences
Background: Family members caring for people living with mental illness (PLWMI) are prone to grapple with caregiver burden. The caregivers often contend with a decline in their mental and physical well-being while executing their role.
Keletwaetse Sakwape, Gaotswake P. Kovane, Precious C. Chukwuere, Miriam Moagi, Rorisang Machailo   +4 more
doaj   +1 more source

The burden of epilepsy and unmet need in people with focal seizures

Brain and Behavior, 2022
Background Epilepsy is one of the most common neurological conditions worldwide. As a chronic condition, epilepsy imposes a significant burden on people with epilepsy and society.
Persefoni Ioannou, Daniella L. Foster, Josemir W. Sander, Sophie Dupont, Antonio Gil‐Nagel, Ewa Drogon O'Flaherty, Elena Alvarez‐Baron, Jasmina Medjedovic   +7 more
doaj   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Advance directives of lung cancer patients and caregivers in China: A cross sectional survey

Thoracic Cancer, 2020
Background This study aimed to investigate lung cancer patients and attitudes of their caregivers toward advance directives (ADs) in China. Methods A cross sectional study was conducted in the Department of Oncology outpatient clinic in West China ...
Chenchen Feng, Juan Wu, Junying Li, Han Yu Deng, Jiewei Liu, Shuzhen Zhao   +5 more
doaj   +1 more source

Knowledge of the Definition of Euthanasia: Study With Doctors and Caregivers of Alzheimer's Disease Patients

, 2009
BACKGROUND: Euthanasia is an increasingly debated subject among specialized professionals and also among lay people, even in countries such as Brazil where it is not authorized.
Caramelli, Paulo, Vilela, Luciana Pricoli   +1 more
core   +1 more source

Effectiveness of psycho-education on knowledge regarding schizophrenia and caregivers’ burden among caregivers of patients with schizophrenia – a randomized controlled trial [PDF]

, 2019
Background. Schizophrenia is one of the commonly occurring disorders, often causing a high degree of disability to the patients, as well as being stressful to the caregivers. Objectives.
Eilean Victoria Lazarus Rathinasamy, Sunanda Govinder Thimmajja, Rathinasamy, Eilean Victoria Lazarus, Thimmajja, Sunanda Govinder   +3 more
core   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source