Results 81 to 90 of about 528,238 (299)

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova   +9 more
wiley   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Knowledge of the Definition of Euthanasia: Study With Doctors and Caregivers of Alzheimer's Disease Patients

open access: yes, 2009
BACKGROUND: Euthanasia is an increasingly debated subject among specialized professionals and also among lay people, even in countries such as Brazil where it is not authorized.
Caramelli, Paulo   +1 more
core   +1 more source

Effectiveness of an Educational Program on Childhood Tuberculosis Supported on Information and Communication Technologies Aimed at Community Mothers from Cartagena

open access: yesInvestigación y Educación en Enfermería, 2016
Objective. To evaluate the effectiveness of an educational program using ICT to improve knowledge on childhood tuberculosis, in Family Women and Childhood (FAMI, for the term in Spanish) of Cartagena (Colombia). Methods.
Irma Yolanda Castillo Avila   +2 more
doaj  

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross‐Sectional Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato   +7 more
wiley   +1 more source

Qualidade de vida em cuidadores de idosos portadores de demência de Alzheimer Quality of life of Alzheimer's disease caregivers' people

open access: yesJornal Brasileiro de Psiquiatria, 2008
OBJETIVO: Realizar revisão sistemática da literatura acerca da QV dos cuidadores de idosos com DA. MÉTODOS: Revisão sistemática de literatura por meio do PubMed e da MedLine entre os anos de 1997 e 2008, utilizando os termos quality of life, caregivers ...
Juliane dos Anjos de Paula   +2 more
doaj   +1 more source

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou   +6 more
wiley   +1 more source

Factors Related to Perceived Needs of Primary Caregivers of Patients with Schizophrenia

open access: yes, 2009
Background/Purpose: Schizophrenia is a chronic mental illness, and sufferers are usually dependent on family, primary caregivers in particular. The present study was designed to assess the perceived needs of caregivers so that adequate services can be ...
Yeh, Ling-Ling; Hwu, Hai-Gwo; Chen, Chun-Houh; Chen, Chen-Hsin; Wu, Agnes C.C.   +1 more
core   +1 more source

Efficacy of a self-help manual in increasing resilience in carers of adults with depression in Thailand [PDF]

open access: yes, 2016
Caring for a person with a mental illness can have adverse effects on caregivers; however, little is known about how best to help such caregivers. The aim of the present study was to examine the efficacy of a cognitive behaviour therapy-guided self-help ...
McCann, Terence V.   +8 more
core   +1 more source

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