Results 91 to 100 of about 293,592 (310)

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

Column generation approaches to ship scheduling with flexible cargo sizes [PDF]

open access: yes
We present a Dantzig-Wolfe procedure for the ship scheduling problem with flexible cargo sizes. This problem is similar to the well-known pickup and delivery problem with time windows, but the cargo sizes are defined by an interval instead of a fixed ...
Nygreen, Bjørn   +2 more
core  

Electrostatic loading and photoredox-based release of molecular cargo from oligoviologen-crosslinked microparticles

open access: yes, 2021
Although on-demand cargo release has been demonstrated in a wide range of microparticle platforms, many existing methods lack specific loading interactions and/or undergo permanent damage to the microparticle to release the cargo. Here, we report a novel
Mark, Palmquist   +6 more
core   +1 more source

Aquaporin‐4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Narcolepsy type 1 (NT1) is caused by the loss of hypocretin‐1 leading to excessive daytime sleepiness and cataplexy. Additionally, disrupted nighttime sleep has become an increasingly recognized feature of NT1. As the glymphatic fluid movement has been linked to sleep architecture, we investigated cerebrospinal fluid (CSF) Aquaporin‐4 (AQP4 ...
Jonas Ranke   +5 more
wiley   +1 more source

Evaluation of ADS-33E Cargo Helicopter Requirements Using a CH-53G

open access: yes, 2006
Flight tests with a Sikorsky CH 53G of the German Federal Armed Forces were conducted in Germany under the U.S./German Memorandum of Understanding (MoU) for Cooperative Research in Helicopter Aeromechanics to evaluate the cargo helicopter requirements of
Blanken, Chris L.   +2 more
core  

The moderating role of transport chain location in cargo theft risk

open access: yes, 2020
Purpose - The purpose of this study is to explore cargo theft risk and security for different product types at different locations along a transport chain.Design/methodology/approach - This study is based on a system-theoretical approach.
Ekwall, Daniel,   +4 more
core   +1 more source

Protein Cargo Encapsulation by Virus-Like Particles: Strategies and Applications

open access: yes, 2022
Viruses and the recombinant protein cages assembled from their structural proteins, known as virus-like particles (VLPs), have gained wide interest as tools in biotechnology and nanotechnology.
Noor, Dashti   +3 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Analysis of Structure of Cargo Turnover at Latvia’s Ports

open access: yes
Ports play a crucially important role in the development of national economy as they generate stable tax flows and duties, providing direct positive effects on GDP, Balance of Payments and Balance of Trade.
Bērziņš, Jānis   +2 more
core   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

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