Results 71 to 80 of about 1,886,374 (304)
Purpose. Increase in the movement speed of railway vehicles makes it possible to strengthen integration processes with the countries of Europe and Asia and leads to the need to improve control, to quantify the dynamic load of rolling stock to ensure safe
A. O. Shvets
doaj +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Development status, technical characteristics and market analysis of large-scale cargo UAVs in China
Large-scale civilian cargo UAVs refer to transport aircraft which can carry heavier and larger cargo and have longer flight times and ranges. They are usually used in fields such as cargo transportation, and material support, and can provide fast, safe ...
WANG Changzhou, LIU Fuhu
doaj +1 more source
Coupling of Active Motion and Advection Shapes Intracellular Cargo Transport
Intracellular cargo transport can arise from passive diffusion, active motor-driven transport along cytoskeletal filament networks, and passive advection by fluid flows entrained by such motor/cargo motion.
H. K. Versteeg +3 more
core +1 more source
Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source
Cargo/Logistics Airlift System Study (CLASS), Executive Summary [PDF]
The current air cargo system is analyzed along with advanced air cargo systems studies. A forecast of advanced air cargo system demand is presented with cost estimates.
Henderson, R. D. +3 more
core +1 more source
Early stages of retinal development depend on Sec13 function [PDF]
Summary ER-to-Golgi transport of proteins destined for the extracellular space or intracellular compartments depends on the COPII vesicle coat and is constitutive in all translationally active cells.
Cavodeassi, Florencia +3 more
core +3 more sources
Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons +31 more
wiley +1 more source
LOGISTIC ACTIVITIES IN BELARUS: TRENDS AND CHALLENGES
Main results of investigations on logistics activities in the Republic of Belarus at year-end 2016 are presented in the paper. The paper identifies and analyzes basic components of this activity on the basis of economic evaluation of indices presented in
P. V. Bozhanov
doaj +1 more source
The role of motor proteins in endosomal sorting [PDF]
Microtubule motor proteins play key roles in the spatial organization of intracellular organelles as well as the transfer of material between them.
Hunt, Sylvie, Stephens, DJ
core +2 more sources

