Results 81 to 90 of about 467 (148)
Bioactive peptides in cancer and inflammation: Mechanisms, model systems and clinical translation
Bioactive peptides (BAPs) derived from host, marine, insect, plant and synthetic sources share cationic, amphipathic structures adopting α‐helical, β‐sheet or cyclic conformations. These features underlie anti‐cancer effects, including membrane disruption, apoptosis and cell‐cycle arrest, anti‐metastatic activity, reduced invasion and migration, and ...
Najwa Doha +4 more
wiley +1 more source
Modular and Adaptive Approach for Advancing Innovation and Sustainability in Light Vehicles Design
This paper reports part of the research results carried out within the National Centre for Sustainable Mobility (MOST—CN4)—Spoke 5 “Light Vehicle and Active Mobility”—funded by the Italian National Recovery and Resilience Plan (PNRR).
Alessandra Rinaldi, Jonathan Lagrimino
doaj +1 more source
The vasculo‐splenic axis during exercise: shear stress triggers the release of medium/large extracellular vesicles from vascular endothelial cells via activation of Piezo1, shuttling Piezo1 to the smooth muscle cells in the splenic capsule; the translocated Piezo1 within the splenic capsule acts as a downstream effector of the α1‐adrenergic receptor ...
Jing Lou +12 more
wiley +1 more source
Urban freight generates a disproportionate share of urban externalities, yet the large-scale integration of eco-friendly vehicles (EFVs) remains limited.
Riccardo Erriu +6 more
doaj +1 more source
On‐Time Meal Delivery Assisted by Drone Resupply
ABSTRACT Ensuring timely delivery is crucial with the increasing competition in online meal delivery services. This requires the industry to adopt new technologies and the corresponding operational models, including the use of drones. Concerning the desired features of meal delivery, such as safety and reliability, we propose an operational model that ...
Wenqian Liu, Lindong Liu, Xiangtong Qi
wiley +1 more source
Barriers to fuel cell cargo bike adoption in urban logistics: a multi-level transition analysis
European municipalities are increasingly pivotal in advancing sustainable urban freight systems. This paper examines the potential of Fuel Cell Cargo Pedelecs (FCCPs) as innovative alternatives to diesel and battery-powered logistics vehicles.
Lara Damer +2 more
doaj +1 more source
Abstract Climate change is a major public health issue in the 21st century, and the links between climate change and health are increasingly becoming recognised by researchers and policy‐makers. Interventions aimed at promoting sustainable behaviours, that is, reducing harmful activities and inducing pro‐environmental action as well as adaptive ...
Walter Leal Filho, Franziska Wolf
wiley +1 more source
ABSTRACT Public service co‐production is often framed as a means of creating public value, yet its dynamics are complex when citizen‐led participation is catalyzed by strong public institutions. This mixed‐methods study examines government‐catalyzed, citizen‐centric co‐production in Shanghai, China, where the state provides institutional support ...
Huanming Wang, Xiaoyun Sun, Bing Ran
wiley +1 more source
Development of pyrazolo[1,5-a]pyrimidine based macrocyclic kinase inhibitors targeting AAK1. [PDF]
Mensing TE +14 more
europepmc +2 more sources

