Exploring Organ-Specific Extracellular Vesicles in Metabolic Improvements Following Bariatric Surgery in Youth With Obesity. [PDF]
Kim A +11 more
europepmc +1 more source
Automated poultry processing lines still rely on humans to lift slippery, easily bruised carcasses onto a shackle conveyor. Deformability, anatomical variance, and hygiene rules make conventional suction and scripted motions unreliable. We present ChicGrasp, an end‐to‐end hardware‐software co‐designed imitation learning framework, to offer a ...
Amirreza Davar +8 more
wiley +1 more source
Exosome profile and composite indices reflect immune exhaustion in periodontitis. [PDF]
Bonilla M, Bravo M, Peñalver I, Mesa F.
europepmc +1 more source
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang +14 more
wiley +1 more source
Trafficking of the human Na<sup>+</sup>/H<sup>+</sup> antiporter NHA2 to the plasma membrane requires cornichon COPII cargo receptors. [PDF]
Kacovská K +7 more
europepmc +1 more source
Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang +7 more
wiley +1 more source
Exosomes-loaded with traditional Chinese medicine constituents: a novel therapeutic avenue for aplastic anemia. [PDF]
Zhang GK, Zhou F.
europepmc +1 more source
A carbon nanotube‐based biopesticide system (BioCNTs) enables efficient delivery and systemic movement of RNAi molecules to control major tomato viruses. By integrating shRNA and tRNA‐like structures (TLS) with BioCNTs, this green and scalable approach achieves long‐term silencing and high antiviral efficacy through simple foliar spraying.
Xuedong Liu +7 more
wiley +1 more source
Machine learning-optimized long single-stranded DNA synthesis technology empowers high-precision diagnostic-therapeutic integration in living cells. [PDF]
Zhang Y +8 more
europepmc +1 more source
Determination of the main parameters of longitudinal vibrations in cargo-transporting devices
In the presented work, the main parameters of cargo-transporting devices with a moving distributed and concentrated inertial load are determined based on a study of longitudinal vibrations of ropes. The oscillations of such systems occur in the form of a superposition of two groups of standing waves with the same frequencies, but different oscillation ...
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