Results 241 to 250 of about 174,123 (272)

RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication

Advanced Science, EarlyView.
Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song, Zuomeng Wu, Yixiang Dong, Yunxiong Fang, Shiyu Bian, Daokuan Wang, Huang Fang, Yunlei Liu, Wang Ying, Jun Qian, Tianyu Han, Cailiang Shen   +11 more
wiley   +1 more source

Investment feasibility and optimization strategies of RFID technology in logistics field. [PDF]

Sci Rep
Han J, Ai H, Li R, Deng X, Wu Y, Wang J, Wei Z.   +6 more
europepmc   +1 more source

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

Advanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie, Songqi Bi, Bang Su, Rongqi Zhou, Xudong Li, Zhixing Yan, Xiaoyang Zhou, Fanxu Wang, Tiecheng Yu   +8 more
wiley   +1 more source

Tissue-Specific Extracellular Vesicles Enriched From Circulation: Exploring the Liquid Biopsy Perspective. [PDF]

J Extracell Biol
Pierri B, Eitan E, Witwer KW, Re DB, Baccarelli AA, Wu H.   +5 more
europepmc   +1 more source

Genome‐Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle‐Mediated siRNA Delivery

Advanced Science, EarlyView.
A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source

Amphibious microneedles for programmable delivery of biomolecules and microorganisms in living plants. [PDF]

Nat Commun
Shen D, Rajappa S, Zhao Y, Pang Z, Li Y, Thenarianto C, Puangpathumanond S, Sevencan C, Lew TTS.   +8 more
europepmc   +1 more source

The Biology of Endosomal Escape: Strategies for Enhanced Delivery of Therapeutics. [PDF]

ACS Nano
Chahal GS, Helbig KJ, Parton RG, Monson EA.   +3 more
europepmc   +1 more source

Applications of Exosomes in Female Medicine: A Systematic Review of Molecular Biology, Diagnostic and Therapeutic Perspectives. [PDF]

Int J Mol Sci
Mariadas H, Chen JH, Chen KH.
europepmc   +1 more source

Molecular basis of the biogenesis of a protein organelle for ethanolamine utilization. [PDF]

Sci Adv
Yang M, Adegbite O, Chang P, Cheng J, Wang Y, Held M, Zhu X, Li Y, Dykes GF, Chen Y, Savage N, Zhang YZ, Gao J, Hinton JCD, Lian LY, Liu LN.   +15 more
europepmc   +1 more source

Biocatalytic 3D binary crystals formed through the self-assembly of enzyme-embedded ferritin.

Nanoscale
Zhou Y, Rosenlöf L, Shen B, Kostiainen MA.   +3 more
europepmc   +1 more source