Results 51 to 60 of about 99,279 (262)

Identifying Systemic Lupus Erythematosus From Serum Proteomic Profiles Using Machine Learning and Genetic Risk Stratification

Arthritis &Rheumatology, EarlyView.
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu, Jishnu Das, Amr H. Sawalha   +2 more
wiley   +1 more source

['Mapping of soil fertility in the municipality of El Rama', 'Mapeo de la fertilidad de los suelos en el municipio de El Rama']

Wani, 2022
Norman Javier Saballos, Kevin Omar Angulo, Macdiel Saúl Amador López , Oscar Armando Sobalvarro Centeno, Engel José Villalta Castillo, Ronaldo González Reyes   +5 more
doaj   +1 more source

Methodological challenges in content‐based citation analysis: Expertise, reliability, and the primacy of citance identification

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Content‐based citation analysis seeks to capture the meaning and functions of citations but continues to face unresolved methodological challenges. This study analyzes a stratified sample of library and information science publications to examine how citance segmentation and annotator expertise influence the consistency of classification ...
Zehra Taşkın
wiley   +1 more source

The role of editorial boards in shaping scholarly communication: A large‐scale mapping of their composition and structure

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Editorial boards play a central role in shaping scholarly communication by influencing what research is published and how disciplinary boundaries are defined. Despite their importance, large‐scale, systematic evidence on their composition and structure remains limited.
Evangelina Becerra‐Rodero, José Luis Ortega   +1 more
wiley   +1 more source

The Effect of Online Parent Training With and Without Coaching Support on the Well‐Being of Families of Children With Neurodisabilities: A Randomized Controlled Trial

Autism Research, EarlyView.
ABSTRACT Families of children with neurodisabilities often face significant child behavioral challenges that can affect overall family functioning and well‐being. This randomized controlled trial (RCT) used family resilience theory as the investigative framework to examine the impact of an online parenting program designed to address child behavioral ...
Jeffrey McCrossin, Ali Filali‐Mouhim, Michael Ungar, Karen McEwan, Kathleen O'Grady, Donna Thomson, Parent Advisory Group, Patricia Lingley‐Pottie, Patrick McGrath, Lucyna M. Lach   +9 more
wiley   +1 more source

Cost‐effectiveness of DPYD genotyping prior to fluoropyrimidine‐based treatment for colorectal cancer in Wales

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background Regulatory guidance in the United Kingdom advises DPYD genotyping prior to fluoropyrimidine‐based treatment. This economic evaluation estimated the costs and outcomes associated with DPYD screening prior to prescribing fluoropyrimidines for colorectal cancer in Wales and also considers additional variants to those included in ...
Catrin O. Plumpton, Sian M. Morgan, Richard A. Adams, Samantha Cox, Angharad A. Rudkin, Megan Fealey, Craig Barrington, Michelle D. Wood, Dyfrig A. Hughes   +8 more
wiley   +1 more source

Estudio de factibilidad para accesos y construcción de puerto de aguas profundas en la Bahía de Bluefields

Ciencia e Interculturalidad
La Bahía de Bluefields es una laguna costera con una gran variedad de ecosistemas que alberga una gran diversidad de flora y fauna. Este ecosistema es altamente vulnerable ante la influencia humana. La Bahía es un sistema marino-costero (estuario).
Nestor J. Gonzalez-Aleman, Billy Francis Ebanks Mongalo, Enoc Geremias Rivas Suazo   +2 more
doaj   +1 more source

UGT1A1 genotype testing for irinotecan: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Abstract Irinotecan, a topoisomerase I inhibitor, is available as both non‐pegylated and pegylated formulations. The non‐pegylated formulation is licensed for use in advanced colorectal cancer either in combination with other agents or as monotherapy.
Dharmisha Chauhan, Cinzia Dello Russo, Jack Thompson, Dyfrig A. Hughes, Katherine Payne, Maria Tsakiroglou, Paul Ross, Rena Chauhan, Simon Jenkinson, Jessica Keen, Sophie Harding, Eleanor Lau, Michael Braun, Roshan Agarwal, Richard Adams, Elisabeth Rolf, Farah Al‐Sheikhli, Sarah Mitchell, Ruth Hammond, Rosie Roberts, Lorna Cairns, Shirley Heggarty, Janet Graham, Justin Mencel, Munir Pirmohamed   +24 more
wiley   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

['Characterization and Biometry of Ichthyofauna in the Laguna of Karata, North Caribbean Coast of Nicaragua', 'Caracterización y Biometría de la Ictiofauna en la Laguna de Karata, Costa Caribe Norte Nicaragüense ']

Wani, 2022
Néstor González-Aleman, Álvaro Mairena-Valdivia, Ennus Isaul Córdoba-Rivera, Otoniel Webster-Logan   +3 more
doaj   +1 more source