Results 121 to 130 of about 2,965,050 (361)
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Necessary Conversation: Faith to Sustain Teaching Practices
In this essay, the author raises critical questions about the need for faith-based teacher preparation programs to consider engaging pre-service teachers in conversations about the connection between faith and the ability to persist in the work of ...
Talley, Stephanie
core
Partnering With Parents and Families to Support Immigrant and Refugee Children at School [PDF]
Describes the mental health needs of immigrant and refugee children and RWJF's Caring Across Communities initiative to support partnerships between schools and families, community organizations, and agencies to address them.
Eileen Gale Kugler
core
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Caring Culture: Art, Architecture and the Politics of Public Health [PDF]
Caring Culture: Art, Architecture and the Politics of Public Health examines changing political uses of the concept of care in neoliberal democracies and asks how artists, architects and designers both contribute to and attempt to critique its social ...
core
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
How Should We Pay the Piper When He's Calling the Tune? On the Long-Term Affordability of Cancer Care in the United States [PDF]
Scott D. Ramsey
openalex +1 more source
Real-time Recognition of Yoga Poses using computer Vision for Smart Health Care [PDF]
Abhishek Sharma +3 more
openalex +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source

