Results 131 to 140 of about 2,965,050 (361)
Pandemic Influenza: Warning, Children At-Risk [PDF]
, 2007 Identifies gaps in U.S. preparedness for treating and caring for children during a potential pandemic flu outbreak. Makes recommendations for appropriate doses of vaccine and medications and the management and treatment of children who become ...
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Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Succession planning: a case for revisiting the process in critical care [PDF]
, 2017 Julie Scholes, Josef Trapani
openalex +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Stressed and Strapped: Caregivers in California [PDF]
, 2011 Profiles the demographics and self-reported physical and mental health status of informal caregivers caring for a family member or friend, including high blood pressure, diabetes, and heart disease; psychological distress; and unhealthy ...
Carolyn Mendez-Luck, Geoffrey J. Hoffman
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Telling 'Billy's story': creating a massive open online course (MOOC) in child and youth care studies [PDF]
, 2016 This poster explores the development of a Massive Open Online Course (MOOC) – Caring for Vulnerable Children – and the way in which it was used to help recruit students to a completely online, distance-learning Masters level programme focused on Child ...
Johnston, Aidan, McPeat, Graham
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Prevention of Mental Illness in primary care [PDF]
, 2005 Evelyn van Weel‐Baumgarten +3 more
openalex +1 more source