Results 101 to 110 of about 8,106,136 (327)

Mifepristone increases mRNA translation rate, triggers the unfolded protein response, increases autophagic flux, and kills ovarian cancer cells in combination with proteasome or lysosome inhibitors [PDF]

open access: yes, 2016
The synthetic steroid mifepristone blocks the growth of ovarian cancer cells, yet the mechanism driving such effect is not entirely understood. Unbiased genomic and proteomic screenings using ovarian cancer cell lines of different genetic backgrounds and
Callegari, Eduardo A.   +13 more
core   +1 more source

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

open access: yesAdvanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente   +5 more
wiley   +1 more source

Pasado, presente y futuro de la Ictiología Argentina. [PDF]

open access: yes, 2007
En este documento se publica la conferencia inaugural del II Simposio de Ictiología: La Perspectiva Neotropical (II SIA), dictada por el Dr.
Menni, Roberto C.
core  

Expression Profiling Analysis Reveals Key MicroRNA– mRNA Interactions in Early Retinal Degeneration in Retinitis Pigmentosa [PDF]

open access: yes, 2018
PURPOSE. The aim of this study was to identify differentially expressed microRNAs (miRNAs) that might play an important role in the etiology of retinal degeneration in a genetic mouse model of retinitis pigmentosa (rd10 mice) at initial stages of the ...
Anasagasti, Ander   +7 more
core   +2 more sources

Nano‐Engineered Titanium Implants Loaded With Gingival Fibroblasts‐Derived Microvesicles Enhance Early Osseointegration And Soft Tissue Attachment In Vivo

open access: yesAdvanced Healthcare Materials, EarlyView.
Our study showed that human primary gingival fibroblast–derived microvesicles on nano‐engineered titanium implants promote early osseointegration and soft‐tissue attachment in vivo. ABSTRACT Titanium dental implants require both reliable osseointegration and peri‐implant soft tissue seal formation to ensure long‐term success. While osseointegration has
Pingping Han   +10 more
wiley   +1 more source

Angiotensin-(1-7) increases osmotic water permeability in isolated toad skin [PDF]

open access: yes, 2000
Angiotensin-(1-7) (Ang-(1-7)) increased osmotic water permeability in the isolated toad skin, a tissue with functional properties similar to those of the distal mammalian nephron. Concentrations of 0.1 to 10 μM were effective, with a peak at 20 min. This
Coviello, Alfredo   +3 more
core   +4 more sources

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney   +3 more
wiley   +1 more source

Astrólogos y astrología al servicio de la monarquía navarra durante la Baja Edad Media (1350-1446)

open access: yesAnuario de Estudios Medievales, 2009
El artículo presenta una visión general de los astrólogos que sirvieron en la corte de Carlos II, Carlos III y Blanca I de Navarra. Un cargo cortesano que unía la adivinación de hechos futuros con la práctica médica del momento.
Fernando Serrano Larráyoz
doaj   +1 more source

La cripta e iglesia de Santa Leocadia y la fábrica del Alcázar de Toledo en el siglo XVI [PDF]

open access: yes, 2009
Las reformas realizadas en el Alcázar de Toledo por iniciativa de Carlos V a partir de 1542 y continuadas por Felipe II, mantienen, en parte, un carácter conservacionista en relación a la antigua disposición y estructura medievales, a excepción, entre ...
Cano de Gardoqui García, José Luis
core   +1 more source

Spiro‐Phenothiazine Hole‐Transporting Materials: Unlocking Stability and Scalability in Perovskite Solar Cells

open access: yesAdvanced Materials, EarlyView.
Fluorene‐functionalized spiro‐phenothiazine (PTZ‐Fl) exhibits strong Li+ affinity and thermal stability, enabling a PCE of 25.75% in small‐area cells and 22.07% in 25 cm2 modules. Under ISOS‐L3 conditions, PTZ‐Flbased devices retain over 80% efficiency after 1000 hours, demonstrating superior stability and scalability compared to spiro‐OMeTAD for next ...
Javier Urieta‐Mora   +17 more
wiley   +1 more source

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