Results 121 to 130 of about 133,759 (327)

Efficacy of omega‐3 fatty acids as a functional food: a multifaceted approach to health reinforcement

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad, Abdulrahman A Alsayegh, Anjum Khanam, Awais Ahmed, António Raposo, Farkad Bantun, Md Zeyaullah, Ahmad O Babalghith, Abdullah F Aldairi, Boshra Mozaffar, Mohammed F Bajahzer, Mohamed H Abdelrahman, Mohammad Intakhab Alam   +12 more
wiley   +1 more source

Etomoxir-carnitine, a novel pharmaco-metabolite of etomoxir, inhibits phospholipases A2 and mitochondrial respiration

Journal of Lipid Research
Mitochondrial fatty acid oxidation serves as an essential process for cellular survival, differentiation, proliferation, and energy metabolism. Numerous studies have utilized etomoxir (ETO) for the irreversible inhibition of carnitine palmitoylcarnitine ...
Sung Ho Moon, Xinping Liu, Christopher M. Jenkins, Beverly Gibson Dilthey, Gary J. Patti, Richard W. Gross   +5 more
doaj   +1 more source

Carnitine and adiponectin levels in breast cancer after radiotherapy

Open Medicine, 2017
In this study, serum carnitine (CRNT) and adiponectin (APN) levels and the correlation of these parameters in patients with breast cancer before and after treatment with radiotherapy (RT) were determined.
Ozmen Hilal Kiziltunc, Erdemci Burak, Askin Seda, Sezen Orhan   +3 more
doaj   +1 more source

Electrokinetic Manipulations Combined With Direct and Ambient Ionization Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) is a powerful analytical technique that typically involves sample preparation and online analytical separation before MS detection. Traditional methods often face bottlenecks in sample preparation and analytical separation, despite the rapid detection capabilities of MS.
Nicholas E. Manicke, Lahiru Wedasingha, Magnus Rydberg   +2 more
wiley   +1 more source

Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury

Med Research, EarlyView.
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang, Yuying Mo, Zhishan Ling, Yuting Zeng, Qi Zhang, Shuqi Zheng, Shuyang Wen, Yupeng Xiao, Siying Long, Tingting Yang, Qianru Li, Wenjie Shi, Guozhi Huang, Qing Zeng   +13 more
wiley   +1 more source

PREVENTION OF HEPATOTOXICITY OF VALPROIC ACID WITH CONCOMITANT SUPPLEMENT OF CARNITINE: AN EXPERIMENTAL STUDY IN ALBINO RATS

Gomal Journal of Medical Sciences, 2014
Background: Valproic acid is an antiepileptic drug which may cause carnitine deficiency and subsequently hepatotoxicity in the form of necrosis and steatosis.
Syed Khanzada Khan, Shahida Tasleem, Naila Ismail, Purdil Khan, Kazi Abdul Shakoor   +4 more
doaj  

Loss‐of‐Function Variants in CPT1C: No Support for a Causal Role in Hereditary Spastic Paraplegia

Movement Disorders, EarlyView.
Abstract Background Hereditary spastic paraplegias (HSPs) are neurodegenerative disorders characterized by lower‐limb spasticity. Pathogenic variants in CPT1C have been implicated in HSP. Objective The objective of this study was to assess whether CPT1C loss‐of‐function (LOF) variants are causally associated with HSP.
Rui Zhu, Lang Liu, Mehrdad A. Estiar, Farnaz Asayesh, Jamil Ahmad, Meron Teferra, Grace Yoon, Mark Tarnopolsky, Kym M. Boycott, Nicolas Dupre, Patrick A. Dion, Oksana Suchowersky, Albena Jordanova, Yi‐Chung Lee, Giovanni Stevanin, Stephan Zuchner, Guy A. Rouleau, Ziv Gan‐Or   +17 more
wiley   +1 more source

EFFECT OF COENZYME Q10 AND L-CARNITINE ON GROWTH PERFORMANCE, PHYSICAL AND CHEMICAL BLOOD INDICES, ANTIOXIDANT STATUS AND IMMUNE RESPONSE OF NEWBORN EGYPTIAN BUFFALO CALVES [PDF]

, 2020
A. Gabr
openalex   +1 more source

A Novel 9‐Channel 1H, 3‐Channel 31P Radiofrequency Coil for Interleaved Multinuclear Studies of Human Calf Muscle at 7 T

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop a double‐tuned calf coil with excellent 1H and 31P performance to study muscle physiology by interleaved 1H/31P MRS and parallel imaging at 7 T. Methods The coil combines three 1H transceive dipoles, six 1H receive‐only loops and three 31P transceive loops, arranged in a nested, half‐cylindrical layout.
Veronika Cap, Vasco Rafael Rocha dos Santos, Kostiantyn Repnin, Onisim Soanca, Elmar Laistler, Peter Wolf, Graham J. Kemp, Roberta Frass‐Kriegl, Martin Meyerspeer   +8 more
wiley   +1 more source

Cats with IRIS stage 1 and 2 chronic kidney disease maintain body weight and lean muscle mass when fed food having increased caloric density, and enhanced concentrations of carnitine and essential amino acids [PDF]

, 2018
Jean A. Hall, Dale A. Fritsch, Dennis E. Jewell, Patricia A Burris, Kathy L. Gross   +4 more
openalex   +1 more source