Results 271 to 280 of about 133,759 (327)

Alternate day fasting alleviates neuroinflammation in diabetic mice by regulating δ-valerobetaine-carnitine-microglia axis via enrichment of Akkermansia muciniphila. [PDF]

Microbiome
Gong K, Zhang S, Pan Y, Cai Q, Wu M, Yin X, Ma J, Ji H, Wang Z, Wu W, Zheng H.   +10 more
europepmc   +1 more source

Proximal Tubule‐Specific Genetic Deficiency of PPARα Worsens Systemic Lipid and Glucose Metabolism During Fasting

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Proximal tubule‐specific PPARα knockout mouse (PPARαΔKPT) showed decreased lipid and glucose metabolism in the kidney during fasting. Metabolism in the other organs was increased, presumably as a means of compensating for the impaired kidney metabolism.
Daiki Aomura, Takayuki Nimura, Kosuke Yamaka, Yosuke Yamada, Makoto Harada, Takero Nakajima, Takefumi Kimura, Koji Hashimoto, Hiroyuki Kanno, Motoko Yanagita, Frank J. Gonzalez, Naoki Tanaka, Yuji Kamijo   +12 more
wiley   +1 more source

Association of Gut Microbiome Biomarkers With Mortality in Chinese Patients With Acute/Worsening Heart Failure. [PDF]

JACC Asia
Suzuki T, Ding H, Yuan F, Li Y, Ren J, Zhan H, Israr MZ, Sun X, Qiu Z, Sheng H.   +9 more
europepmc   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, Volume 600, Issue 1, Page 20-38, January 2026.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Dentz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source

Neuroinflammation-Modulating Properties Combining Glutathione, N-Acetylcysteine, and Uridine Monophosphate in a Formulation Supplement: An In Vitro Study. [PDF]

Brain Sci
Mulè S, Parini F, Galla R, Uberti F.
europepmc   +1 more source

Adenylosuccinate Synthase 1 Deficiency Improves Energy Metabolism by Promoting Adipose Tissue Re‐esterification via Glycerol Kinase Upregulation

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun, Miriayi Alimujiang, Wenfei Li, Shuqin Chen, Yingying Su, Tingting Hu, Xuhong Lu, Yafen Ye, Ningning Bai, Fan Hu, Xiaoya Li, Rongrong Xu, Jun Xu, Jiarui Zhao, Yan Lu, Xiaojing Ma, Ying Yang   +16 more
wiley   +1 more source

L-carnitine: new perspectives on the management of preterm infants. [PDF]

Front Nutr
Sisi M, Yong L, Lixing Q, Changsheng G, Jin Y, Hang Z, Xing C, Heng L.   +7 more
europepmc   +1 more source

CIDEC Restricts Liver Regeneration by Disturbing Lipid Droplet Triglyceride Turnover

Advanced Science, Volume 13, Issue 3, 14 January 2026.
This study identifies CIDEC, an lipid droplet (LD)‐fusion associated protein upregulated by CREBH during early regeneration, as a negative regulator of liver regeneration through its unexpected role in sequestering triglyceride (TG) within LDs. CIDEC depletion reduces LD size, mobilizes LD‐stored TG, enhances TG catabolism and free fatty acid (FFA ...
Feng Ouyang, Yining Li, Zixuan Zhang, Fangfang Sun, Yihong Shi, Qian Gui, Da Luo, Changyong Hu, Hang Su, Kaiqi Shen, Lu Gao, Hui Yang, Feng‐Jung Chen, Rong Li, Tong‐Jin Zhao, Peng Li, Tian‐Shu Yang   +16 more
wiley   +1 more source

Progressive Weakness in Adulthood: Lipid Storage Myopathy With Suspected Sertraline-Associated Etiology. [PDF]

Cureus
Feely J, Saliba N, Nze N, Nguyen J.
europepmc   +1 more source

Iron Overload Mediates the Differential Cell Fate of Astrocytes from Neurons and Its Regulatory Mechanisms in Ischemic Stroke

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Upon ischemia/reperfusion‐induced iron overload condition, neurons and astrocytes exhibit similar oxidative stress changes but opposite alterations in endogenous antioxidant defense mechanisms, leading to divergent ferroptotic outcomes. The iron deposition and neuronal loss are increased within the perilesional cortex of stroke patients ...
Yi Guo, Yue Wang, Yong Ni, Bin Bo, Jinzhi He, Yongming Zhu, Aiping Qin, Xianyong Zhou, Huaping Du, Yuan Liu, Tianyao Wang, Yudu Li, Yibo Zhao, Zengai Chen, Zhipei Liang, Yao Li, Yuan Xu, Huiling Zhang   +17 more
wiley   +1 more source