Results 281 to 290 of about 162,227 (374)

HEPES in Cell Culture Alters the Multi‐Omics Profile Exhibited by Gaucher Disease Fibroblasts

Journal of Cellular Biochemistry, Volume 127, Issue 1, January 2026.
ABSTRACT Lysosomal function can be affected by components in cell culture. This in turn may influence cellular metabolism and, consequently, research and diagnostics outcomes. One such component is the commonly used pH buffer 4‐(2‐hydroxyethyl)‐1‐piperazineethanesulfonic acid (HEPES).
Eleonore M. Corazolla, Bauke V. Schomakers, Maria M. Trętowicz, Jill Hermans, Michel van Weeghel, Frédéric M. Vaz, Mia L. Pras‐Raves, Karen Ghauharali‐van der Vlugt, Femke S. Beers‐Stet, Susanna M. I. Goorden, Judith Jansen‐Meijer, Georges E. Janssens, Carla E. M. Hollak, Riekelt H. Houtkooper, André B. P. van Kuilenburg   +14 more
wiley   +1 more source

Predictive Role of Metabolic Profiling in Rivaroxaban Efficacy for Thrombus Lysis in Atrial Fibrillation. [PDF]

Int J Mol Sci
Michorowska S, Korytowska-Przybylska N, Piotrowski R, Kułakowski P, Giebułtowicz J.   +4 more
europepmc   +1 more source

Inhibition of carnitine palymitoyltransferase1b induces cardiac hypertrophy and mortality in mice

, 2013
Kimberly R. Haynie, Bolormaa Vandanmagsar, Shawna Wicks, J. Zhang, Randall L. Mynatt   +4 more
openalex   +2 more sources

Nutritional Management in Severe Methylmalonic and Propionic Acidemias: How Much Medical Food Is Too Much?

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT Methylmalonic acidemia (MMA) and propionic acidemia (PA) are inherited metabolic disorders affecting valine and isoleucine catabolism. Long‐term therapy mainly involves dietary protein restriction. An amino acid mixture (AAM, medical food) free of the precursor amino acids is frequently used, especially when protein intake does not reach World
Diane Margoses, Apolline Imbard, Clément Pontoizeau, Anaïs Brassier, Jean‐Baptiste Arnoux, Juliette Bouchereau, Claire‐Marine Bérat, Murielle Assoun, Claire Belloche, Sabine Dewulf, Sandrine Dubois, Bénédicte Samba, Aude Servais, Myriam Dao, Edouard Le Guillou, Amélie de Colnet, Chris Ottolenghi, Pascale de Lonlay, Jean‐François Benoist, Manuel Schiff   +19 more
wiley   +1 more source

Rare case of respiratory syncytial virus induced myocarditis in a neonate: A case report. [PDF]

World J Clin Pediatr
Jaber LSK, Abu-Hamdeh M, Qouqas M, Abdullah J, Asad RM, Manhal A, Yadak DGM.   +6 more
europepmc   +1 more source

L-Carnitine supplementation reduces the general fatigue of cancer patients during chemotherapy

, 2018
Hiroki Matsui, Takahiro Einama, Shunsuke Shichi, Ryo Kanazawa, Kazuaki Shibuya, Takashi Suzuki, Fumihiko Matsuzawa, Taku Hashimoto, Shigenori Homma, Junji Yamamoto, Akinobu Taketomi, Hironori Abe   +11 more
openalex   +2 more sources

Untargeted Metabolomics for Diagnosis, Monitoring, and Understanding the Pathophysiology of Inherited Metabolic Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT Inherited metabolic disorders (IMDs) encompass a diverse and expanding group of rare diseases caused by genetic disruptions mainly in metabolic enzymes and transporters. Clinical diagnosis of IMDs presents significant challenges due to phenotypic heterogeneity, nonspecific symptoms, and the limited scope of current targeted biochemical assays ...
Jonathan Martens, Udo F. H. Engelke, Ron A. Wevers, Dirk J. Lefeber, Purva Kulkarni   +4 more
wiley   +1 more source

Carnitine

EMC - Biologie Médicale, 2006
openaire   +3 more sources

Octanoyl-carnitine predicts post operative complications following coronary artery bypass surgery. [PDF]

Sci Rep
Bahr PA, De Barros JP, Lemaire-Ewing S, Berthoud V, Bouhemad B, Masson D, Nguyen M, Guinot PG.   +7 more
europepmc   +1 more source

The role of L-carnitine in the pathogenesis of cardiomegaly in patients with chronic hemodialysis.

, 1983
Yasuo Kudoh, Tetsuro Shoji, Hiroshi Oimatsu, Shigeo Yoshida, Kenjiro Kikuchi, Osamu Iimura   +5 more
openalex   +2 more sources