Results 1 to 10 of about 1,621 (128)

High frequency of CD95⁺/CD45RA^- regulatory T cells defines an immunosuppressive profile associated with MDS progression. [PDF]

Br J Haematol
Summary Dynamic interactions between mutated haematopoietic cells and immune cells are key drivers of myelodysplastic neoplasms (MDS) initiation and progression. Regulatory T cells (Tregs) are central mediators of immunosuppression in MDS. We thus aimed to characterize Treg subpopulations in the bone marrow (BM) of MDS patients and to explore their ...
Vazquez R, Deredec N, Boussaid I, Boncoeur P, Knosp C, Houvert A, Zalmai L, Friedrich C, Almire C, Dussiau C, Willems L, Birsen R, Decroocq J, Bouscary D, Kosmider O, Kordasti S, Fontenay M, Simoni Y, Chapuis N.   +18 more
europepmc   +2 more sources

Bioconjugation Strategies for Revealing the Roles of Glycerophospholipids in Cells. [PDF]

Chembiochem
Glycerophospholipids are the main class of phospholipids, essential for membrane structure, compartmentalization, and cellular signaling. To study their roles, innovative probes and advanced bioconjugation strategies have been developed, including by de novo lipid synthesis and bioorthogonal conjugation chemistry.
Beauvais B, Rohokale R, Mamputu S, Lupu I, Guo Z, Balieu S.   +5 more
europepmc   +2 more sources

<i>CEBP</i> and <i>ZEB2</i> alterations define three distinct subtypes of B-cell acute lymphoblastic leukemia. [PDF]

Hemasphere
Abstract B‐cell acute lymphoblastic leukemia (B‐ALL) is a heterogeneous malignancy driven by diverse genetic alterations. Among these, CEBP family genes and ZEB2 are recurrently involved, yet the spectrum of genomic mechanisms and their clinical impact remain incompletely defined.
Kim R, Passet M, Bergugnat H, Vasseur L, Leguay T, Huguet F, Hunault M, Sexton T, Benlebna M, Renard J, Raffoux E, Pastoret C, Erb C, Chat L, Delabesse E, Gachet S, Bonmati C, Balsat M, Braun T, Bidet A, Duployez N, Graux C, Chalandon Y, Rousselot P, Chevallier P, Soulier J, Lhéritier V, Dombret H, Boissel N, Clappier E.   +29 more
europepmc   +2 more sources

Identifying 1-rectifiable measures in Carnot groups

Analysis and Geometry in Metric Spaces, 2023
We continue to develop a program in geometric measure theory that seeks to identify how measures in a space interact with canonical families of sets in the space. In particular, extending a theorem of M. Badger and R.
Badger Matthew, Li Sean, Zimmerman Scott
doaj   +1 more source

Exceptional families of measures on Carnot groups

Analysis and Geometry in Metric Spaces, 2023
We study the families of measures on Carnot groups that have vanishing pp-module, which we call Mp{M}_{p}-exceptional families. We found necessary and sufficient Conditions for the family of intrinsic Lipschitz surfaces passing through a common point to ...
Franchi Bruno, Markina Irina
doaj   +1 more source

A Cornucopia of Carnot Groups in Low Dimensions

Analysis and Geometry in Metric Spaces, 2022
Stratified groups are those simply connected Lie groups whose Lie algebras admit a derivation for which the eigenspace with eigenvalue 1 is Lie generating.
Le Donne Enrico, Tripaldi Francesca
doaj   +1 more source

On the H.-Q. Li inequality on step-two Carnot groups

Comptes Rendus. Mathématique, 2023
In this note we show that the gradient estimate of the heat semigroup, or more precisely the H.-Q. Li inequality, is preserved under tensorization, some suitable group epimorphism, and central sum. We also establish the Riemannian counterpart of the H.-Q.
Zhang, Ye
doaj   +1 more source

Sharp Hardy Identities and Inequalities on Carnot Groups

Advanced Nonlinear Studies, 2021
In this paper we establish general weighted Hardy identities for several subelliptic settings including Hardy identities on the Heisenberg group, Carnot groups with respect to a homogeneous gauge and Carnot–Carathéodory metric, general nilpotent groups ...
Flynn Joshua, Lam Nguyen, Lu Guozhen
doaj   +1 more source

Hilbert-Haar coordinates and Miranda's theorem in Lie groups

Bruno Pini Mathematical Analysis Seminar, 2020
We study the interior regularity of solutions to a class of quasilinear equations of non-degenerate p-Laplacian type on Lie groups that admit a system of Hilbert-Haar coordinates. These are coordinates with respect to which every linear function has zero
András Domokos, Juan J. Manfredi
doaj   +1 more source

On Viscosity and Equivalent Notions of Solutions for Anisotropic Geometric Equations

Abstract and Applied Analysis, 2020
We prove that viscosity solutions of geometric equations in step two Carnot groups can be equivalently reformulated by restricting the set of test functions at the singular points.
Cecilia De Zan, Pierpaolo Soravia
doaj   +1 more source