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Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque [PDF]
, 2011 Carotid intima media thickness (cIMT) and plaque determined by ultrasonography are established measures of subclinical atherosclerosis that each predicts future cardiovascular disease events.Taylor, K, Rice, K. (Kenneth), Petrovic, K. (Katja), Orru, M, Meisinger, C. (Christa), Fox, Caroline S., Ralph B D'Agostino, Ballantyne, C. (Christie), Rivadeneira Ramirez, F. (Fernando), Demissie, S, Sanna, Serena, Harris, Tamara B, Markus, Hugh S, Petrovic, KE, Huffman, J.E. (Jennifer), White, C.C. (Charles), Heiss, G. (Gerardo), Sanna, S, Eiriksdottir, Gudny, Newman, Anne B, Peltonen, L, Smith, AV, Huffman, JE, Couper, DJ, Huffman, Jennifer E., Blankenberg, Stefan, Baumert, J. (Jens), Lüdemann, Jan, Reinhold Schmidt, Arne Schillert, Sitzer, M, Dörr, M. (Marcus), Manuela Uda, Steve Bevan, Serkalem Demissie, Boerwinkle, Eric, Xia Li, O'Leary, Daniel H, Eiriksdottir, G, Ulf Schminke, O'Donnell, CJ, Wichmann, H.E. (Heinz Erich), Kavousi, M, Halperin, E, Boerwinkle, E, Illig, T. (Thomas), Heiss, G, Heckbert, Susan R, Bis, JC, Tamara B Harris, Harris, T.B. (Tamara), Smith, Albert V, Launer, Lenore J, Ziegler, A, Schmidt, Reinhold, Heckbert, Susan R., Meisinger, Christa, Wild, P.S. (Philipp), Polak, Joseph F., Klopp, Norman, Cupples, L.A. (Adrienne), Joseph F Polak, Aspelund, T. (Thor), Wolf, PA, Couper, David J., Alan R Shuldiner, White, Charles C, Rivadeneira, F, Homuth, G, Gonçalo R Abecasis, Cheng, YC, Maryam Kavousi, Taylor, Kent, White, CC, Li, X. (Xia), ?, ?, Orru, Marco, Wild, PS, Bevan, S, Duijn, Cornelia, Wendy S Post, Abbas Dehghan, Halperin, E. (Eran), Luedemann, Jan, Smith, A.V. (Albert Vernon), Münzel, T, Franceschini, N. (Nora), Kähönen, M, Stoegerer, EM, Baumert, Jens, Reilly, Muredach P., Thomas Illig, Völzke, H. (Henry), Homuth, G. (Georg), D'Agostino, RB, Lenore J Launer, Schminke, Ulf, Christie Ballantyne, Franceschini, N, Uda, Manuela, Wild, Philipp S, Scuteri, Angelo, Huffman, Jennifer E, Rice, Kenneth, Hugh S Markus, Christopher J O'Donnell, Launer, Lenore J., Usala, G, Fernando Rivadeneira, Jacqueline Witteman, Post, WS, Norman Klopp, Gudnason, V. (Vilmundur), Petrovic, Katja E., Mitchell, BD, Uitterlinden, Andre, Post, W.S. (Wendy S.), Wolf, Philip A, Reilly, M.P. (Muredach), Rotter, Jerome I, Franceschini, Nora, Newman, Anne B., Andreas Ziegler, Marco Orru, Uitterlinden, A, Fox, CS, Dörr, Marcus, Schnabel, R.B. (Renate), Edward G Lakatta, Nambi, Vijay, Isaacs, Aaron; id_orcid, Cheng, Yu-Ching, Uitterlinden, A.G. (André), Ben Oostra, Wilson, James F, Stefan Blankenberg, Schmidt, Helena, O'Donnell, C.J. (Christopher), Koenig, W, Völzke, H, Reilly, MP, Thomas Münzel, Mika Kähönen, Dehghan, Abbas, Gudnason, V, Bevan, Steve, Raitakari, O, Thorsson, Bolli, Yu-Ching Cheng, Isaacs, A.J. (Aaron), Caroline S Fox, Koenig, Wolfgang, Albert V Smith, Cupples, LA, Rathmann, W, Bruce M Psaty, Andre Uitterlinden, Zeller, T, Smith, Albert V., Shuldiner, Alan R, Florian Ernst, Ballantyne, C, Kavousi, M. (Maryam), Chilukoti, R.K. (Ravi Kumar), Ziegler, Andreas, Duijn, CV, Schillert, A, Lakatta, Edward G., Psaty, B.M. (Bruce), Homuth, Georg, Harris, TB, O'Leary, D.H. (Daniel H.), Ernst, Florian, Raitakari, Olli, Post, Wendy S, Shuldiner, AR, Demissie, S. (Serkalem), Abecasis, GR, Oostra, B.A. (Ben), Schnabel, RB, Joshua C Bis, Wilson, James F., Kathiresan, S. (Sekar), Gerardo Heiss, Thor Aspelund, Hofman, Albert, Eric Boerwinkle, Illig, Thomas, Mitchell, B.D. (Braxton), Schillert, Arne, Hayward, C, Voelzke, Henry, North, K, Polak, Joseph F, Polak, JF, Halperin, Eran, Lehtimäki, T. (Terho), Tanja Zeller, Lakatta, E. (Edward), Joachim Thiery, Helena Schmidt, David J Couper, Aaron Isaacs, Demissie, Serkalem, Rotter, JI, Seissler, J. (Jochen), Petrovic, Katja E, Chilukoti, Ravi Kumar, Duijn, C.M. (Cornelia) van, Thiery, Joachim, Thorsson, B. (Bolli), Schillert, A. (Arne), Psaty, Bruce M., Mitchell, Braxton D., Henry Völzke, Kenneth Rice, Lüdemann, J, Lehtimaki, Terho, Isaacs, A, Marcus Dörr, Matthias Sitzer, Witteman, Jacqueline, Uda, M. (Manuela), Bis, Joshua C, Lehtimäki, T, Shuldiner, A.R. (Alan), Bevan, S. (Steve), null null, Serena Sanna, H Erich Wichmann, Lakatta, EG, Abecasis, G.R. (Gonçalo), Parsa, Afshin, Bis, J.C. (Joshua), Uda, M, Wichmann, H Erich, Blankenberg, S. (Stefan), Shuldiner, Alan R., Anne B Newman, Hofman, Bert, North, Kari, Thiery, J.P. (Joachim), Dörr, M, Afshin Parsa, Vijay Nambi, Zeller, Tanja, Schminke, U. (Ulf), Chilukoti, RK, Leena Peltonen, Rotter, J.I. (Jerome), Psaty, Bruce M, Heckbert, SR, Dehghan, A, Nambi, V, Witteman, J, Polak, J.F. (Joseph F.), Jorma Viikari, Kari North, Eran Halperin, Daniel H O'Leary, Wolf, Philip A., Seissler, Jochen, Usala, G., O'Leary, DH, Heckbert, S.R. (Susan), Ballantyne, Christie, Nora Franceschini, North, K.E. (Kari), Jennifer E Huffman, Jan Lüdemann, Vilmundur Gudnason, Meisinger, C, Jens Baumert, Rivadeneira, Fernando, Ziegler, A. (Andreas), O'Donnell, Christopher J., Eiriksdottir, G. (Gudny), Kathiresan, S, Wolf, P.A. (Philip), Cheng, Y.C. (Yu Ching), van Duijn, Cornelia, Rathmann, Wolfgang, Wolfgang Koenig, Zeller, T. (Tanja), Peltonen, Leena, Kent Taylor, Kähönen, M. (Mika), D'Agostino, Ralph B, Olli Raitakari, Völzke, Henry, Ernst, F, Mitchell, Braxton D, Wichmann, HE, Heiss, Gerardo, Muenzel, Thomas, Abecasis, Goncalo R., Koenig, W. (Wolfgang), James F Wilson, Viikari, J. (Jorma), Wilson, James F; id_orcid, Boerwinkle, E.A. (Eric), Susan R Heckbert, Markus, HS, Seissler, J, Bis, Joshua C., O'Leary, Daniel H., Klopp, N, Ravi Kumar Chilukoti, Stoegerer, E.M. (Eva Maria), Usala, Gianluca, Fox, C.S. (Caroline), Caroline Hayward, Harris, Tamara B., Li, X, Parsa, A, Jochen Seissler, Abecasis, Gonçalo R, Illig, T, Jerome I Rotter, Cupples, L Adrienne, Cupples, L. Adrienne, Launer, LJ (Lenore), Gudnason, Vilmundur, Lakatta, Edward G, Schmidt, R, Scuteri, A, Bolli Thorsson, Stoegerer, Eva-Maria, Uitterlinden, André; id_orcid, Post, Wendy S., Schmidt, R. (Reinhold), Schmidt, H, Kahonen, Mika, Cornelia van Duijn, Angelo Scuteri, Philipp S Wild, Viikari, J, Schnabel, Renate B, Baumert, J, Peltonen, L. (Leena Johanna), Renate B Schnabel, Sekar Kathiresan, Muredach P Reilly, D'Agostino, Ralph Sr., Rice, K, Philip A Wolf, Parsa, A. (Afshin), Doerr, Marcus, Orrù, M. (Marco), White, Charles C., Dehghan, A. (Abbas), Hayward, Caroline, Hofman, A. (Albert), Münzel, Thomas, Witteman, JCM, Blankenberg, S, Albert Hofman, Schnabel, Renate B., O'Donnell, Christopher J, D'Agostino, Ralph B., Sr., Sitzer, Matthias, CARDIoGRAM Consortium, Katja E Petrovic, Viikari, Jorma, Oostra, B, Ernst, F.D.J. (Florian), Aspelund, T, Rathmann, W. (Wolfgang), D'Agostino, R.B. (Ralph), Couper, D.J. (David), Couper, David J, Thorsson, B, Psaty, BM, Wolfgang Rathmann, Hayward, C. (Caroline), Oostra, Ben, Aspelund, Thor, Reilly, Muredach P, Georg Homuth, Markus, H.S. (Hugh S.), Lüdemann, J. (Jan), Gianluca Usala, Taylor, K.D. (Kent), Isaacs, Aaron, Wichmann, H. Erich, Raitakari, O. (Olli), Hofman, A, Kathiresan, Sekar, Wilson, JF, Launer, L.J. (Lenore), Markus, Hugh S., Schminke, U, Charles C White, Launer, LJ, Thiery, J, Sanna, S. (Serena), Duijn, Cornelia van, Newman, AB, Newman, A.B. (Anne), Christa Meisinger, Witteman, J.C.M. (Jacqueline), Klopp, N. (Norman), Wild, Philipp S., Wilson, J.F. (James), Eva-Maria Stoegerer, Hayward, Caroline; id_orcid, Kavousi, Maryam, Nambi, V. (Vijay), Sitzer, M. (Matthias), Rotter, Jerome I., Münzel, T. (Thomas), Gudny Eiriksdottir, Braxton D Mitchell, L Adrienne Cupples, Terho Lehtimäki, Li, Xia, Scuteri, A. (Angelo), Fox, Caroline S +417 morecore +1 more sourceCarotid stiffness and physical activity in elderly : a short report of the SAPALDIA 3 cohort study [PDF]
, 2015 Regular physical activity has been shown to reduce cardiovascular disease risk in the general population. While smaller studies in specified groups (highly trained versus untrained individuals) indicate a certain dose-dependent effect of physical ...Wanner, Miriam, Arno Schmidt-Trucksäss, Autenrieth, Christine S, Simon Endes, Emmanuel Schaffner, Christian Schindler, Eric de Groot, Jean-Michel Gaspoz, Dratva, Julia, Julia Dratva, Martin, Brian, Christine S Autenrieth, de Groot, Eric, Probst-Hensch, Nicole, Christine S. Autenrieth, Miriam Wanner, Künzli, Nino, Schmidt-Trucksäss, Arno, Nino Künzli, Endes, Simon, Autenrieth, Christine S., Seraina Caviezel, Schaffner, Emmanuel, Nicole Probst-Hensch, Schindler, Christian, Gaspoz, Jean-Michel, Brian Martin, Caviezel, Seraina +27 morecore +2 more sourcesOptimal cut-off criteria for duplex ultrasound for the diagnosis of restenosis in stented carotid arteries: Review and protocol for a diagnostic study [PDF]
, 2009 Background: Carotid angioplasty with stenting is a relatively new, increasingly used, less-invasive treatment for the treatment of symptomatic carotid artery stenosis. It is being evaluated in ongoing and nearly finished randomized trials.Brown, Martin M., Nederkoorn, Paul J., Paul J Nederkoorn, Nederkoorn Paul J, Brown, M.M., Martin M Brown, Brown, MM, Nederkoorn, P.J., Brown Martin M, Nederkoorn, PJ +9 morecore +3 more sourcesTiming of procedural stroke and death in asymptomatic patients undergoing carotid endarterectomy: individual patient analysis from four RCTs [PDF]
, 2020 BACKGROUND: The effectiveness of carotid endarterectomy (CEA) for stroke prevention depends on low procedural risks. The aim of this study was to assess the frequency and timing of procedural complications after CEA, which may clarify underlying ...Algra, A, Brott, TG, Eckstein, H-H, Halliday, A, Calvet, D, Morris, Dylan R, Morris, DR, Hendrikse, J, Rothwell, Peter M, Pan, Hongchao, Bulbulia, Richard, Bulbulia, R, Carotid Stenosis Trialists' Collaboration, Mas, J-L, Brown, MM, Halliday, Alison, Bonati, LH, Rothwell, PM, Fraedrich, G, Poorthuis, MHF, Gregson, J, Greving, JP, Lewis, SC, Jansen, O, Howard, G, de Borst, GJ, Pan, H, Poorthuis, Michiel HF, Becquemin, J-P +28 morecore +1 more sourceAssociation between Inguinal Hernia and Arterial Disease: A Preliminary Report
Biology, 2021 Background: Inguinal hernia (IH) is a major problem in general surgery and its prevalence is increasing. The presence of hernias has been associated with a wide spectrum of venous diseases, with the involvement of imbalances in collagen and extracellular Raffaele Serra, Umberto Marcello Bracale, Rosy Conforto, Arturo Roncone, Nicola Ielapi, Ashour Michael, Maurizio Sodo, Maria Donata Di Taranto, Pasquale Mastroroberto, Giuseppe Filiberto Serraino, Michele Provenzano, Michele Andreucci +11 moredoaj +1 more sourceCommon carotid intima media thickness and ankle-brachial pressure index correlate with local but not global atheroma burden:a cross sectional study using whole body magnetic resonance angiography [PDF]
, 2014 Common carotid intima media thickness (CIMT) and ankle brachial pressure index (ABPI) are used as surrogate marker of atherosclerosis, and have been shown to correlate with arterial stiffness, however their correlation with global atherosclerotic burden ...Belch, Jill J. F.; id_orcid, Belch, Jill J F, Faisel Khan, Stephen J Gandy, Gardner, Michael, Weir-McCall, Jonathan R., Rauchhaus, Petra, Adamson, Carly L., Gandy, Stephen J., Gandy Stephen J., Morris, Andrew D., Rauchhaus Petra, Houston, J. Graeme, Allan D Struthers, Lambert, Matthew A., Matthew A Lambert, J Graeme Houston, Ramkumar Prasad Guntur, Struthers Allan D., Lambert Matthew A., Gardner Michael, Adamson Carly L., Jill J F Belch, Michael Gardner, Khan, Faisel; id_orcid, Petra Rauchhaus, Weir-McCall Jonathan R., Jonathan R Weir-McCall, Khan Faisel, Ramkumar, Prasad Guntur, Khan, Faisel, Belch Jill J. F., Morris Andrew D., Carly L Adamson, Struthers, Allan D., Houston J. Graeme, Andrew D Morris, Prasad Guntur Ramkumar +37 morecore +2 more sourcesMicrobiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille +3 morewiley +1 more source