Results 61 to 70 of about 369,680 (255)

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

IMPACT OF THE ANESTHETIC METHOD ON LIPID PEROXIDATION ACTIVITY DURING CAROTID ENDARTERECTOMY

open access: yesВестник анестезиологии и реаниматологии, 2018
The objective of the study: to assess the effect of two types of general anesthesia on lipid peroxidation and to establish a correlation between the degree of its activation and the number of post-operative neurological disorders.Subjects and methods ...
M. I. Neymark   +3 more
doaj   +1 more source

Automated IMT estimation and BMI correlation using a low-quality carotid ultrasound image database from India. [PDF]

open access: yes, 2013
This paper presents AtheroEdgeLowRes (AELR), an extention of AtheroEdge™ from AtheroPoint™, and a solution to carotid ultrasound IMT measurement in low-resolution and overall low quality images.
Saba, Luca   +48 more
core   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau   +11 more
wiley   +1 more source

Acellular carotid scaffold and evaluation the biological and biomechanical properties for tissue engineering [PDF]

open access: yesJournal of Cardiovascular and Thoracic Research
Introduction: The issues associated with the limitation of appropriate autologous vessels for vascular reconstruction via bypass surgery highlight the need for new alternative strategies based on tissue engineering.
Farina Rashidi   +4 more
doaj   +1 more source

Vulnerable Carotid Artery Plaques in Asymptomatic Patients—A Narrative Review

open access: yesThe Arab Journal of Interventional Radiology, 2022
Over the last two decades, medical management of carotid artery patients has improved significantly. Most patients remain stable on best medical therapy (BMT), making interventions unnecessary in all patients.
Zia Ur Rehman
doaj   +1 more source

Modern Management of Asymptomatic Carotid Stenosis: A Meta‐Analysis of CREST‐2, SPACE‐2, and ECST‐2

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Recent randomized trials (CREST‐2, SPACE‐2, and ECST‐2) have compared carotid revascularization (carotid endarterectomy [CEA] or carotid artery stenting [CAS]) plus contemporary medical therapy (CMT) versus CMT alone in asymptomatic carotid stenosis.
Aasim Ali   +14 more
wiley   +1 more source

Delayed Cavernous Carotid Artery Pseudoaneurysm Caused by Absorbable Plate Following Transsphenoidal Surgery: Case Report and Review of the Literature

open access: yesJournal of Neurological Surgery Reports, 2013
Background Bioabsorbable plates are frequently utilized in the repair of skull base defects following transsphenoidal operations. Traumatic intracranial pseudoaneurysms are a rare complication of transsphenoidal surgery.
Alexander Tuchman   +4 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Cross‐Sectional Validation of a Novel Computed Tomography‐Based Carotid Mean Calcium Density Measurement

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background The purpose of this study was to validate a technique for measuring mean calcium density and to determine associations of cardiovascular risk factors with carotid calcium density.
Rachel Cahalane   +6 more
doaj   +1 more source

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