Results 111 to 120 of about 76,930 (215)

Enhanced Drug Effect With Cutting Balloon Followed by Drug Coated Balloon in a Rabbit Model

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Drug‐coated balloon (DCB) are effective treatment options for patients with coronary artery disease and using of scoring or cutting balloon before the DCB usage were recommended. However, the effectiveness of lesion preparation with cutting balloons (CB) followed by DCB (CB + DCB) has not been evaluated before.
Manabu Shiozaki, Sho Torii, Yu Sato, Kazuki Aihara, Yuki Matsumoto, Norihito Nakamura, Daiki Suzuki, Ayako Yoshikawa, Yuji Ikari, Gaku Nakazawa   +9 more
wiley   +1 more source

Optical Coherence Tomography for Cervical Artery Dissection

Annals of Neurology, EarlyView.
Guangxun Shen, Jingmin Zhao, Ying Mao, Guangxian Nan   +3 more
wiley   +1 more source

Impact of Elevated Preprocedural Left Ventricular Filling Pressure on Prognosis of Mild Paravalvular Regurgitation Following Transcatheter Aortic Valve Replacement

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Paravalvular regurgitation (PVR) following transcatheter aortic valve replacement (TAVR) is a complication linked to poor outcomes. The prognostic impact of mild PVR, particularly in patients with elevated preprocedural left ventricular (LV) filling pressure, remains uncertain.
Shumpei Kosugi, Isamu Mizote, Daisuke Nakamura, Hiroki Sugae, Yutaka Matsuhiro, Shota Okuno, Ai Kawamura, Kizuku Yamashita, Koichi Maeda, Kazuo Shimamura, Tomoharu Dohi, Yasuharu Takeda, Yasushi Sakata   +12 more
wiley   +1 more source

Using Shockwave Lithotripsy to Treat Severe Calcified Mitral Stenosis in a Pregnant Woman

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Rheumatic mitral stenosis (MS) with significant calcification presents challenges for both surgical and transcatheter interventions. Percutaneous balloon mitral valvuloplasty (PBMV) is often limited in these cases due to valve rigidity, increasing the risk of mitral regurgitation (MR).
Mhd Baraa Habib, Cheikh Ahmed Aboulmaaly, Nazar Mohammed, Mohammed Al‐Hijji   +3 more
wiley   +1 more source

Evaluation of NaTto Red Yeast Rice on Regulating Blood Lipid (ENTRY) Study: A Multicenter, Double‐Placebo, Double‐Blinded, Randomized Controlled Trial in Chinese Adults

Chronic Diseases and Translational Medicine, EarlyView.
Study flow chart of the ENTRY study. ABSTRACT Background Statins are the first line of treatment for dyslipidemia, but their side effects often reduce medication compliance. Natto and red yeast rice are natural ingredients with lipid‐lowering effects.
Shufeng Chen, Fangchao Liu, Jinyue Li, Fengchao Liang, Jianxin Li, Jie Cao, Donghua Liu, Keyong Huang, Hongfan Li, Xiangfeng Lu, Jianfeng Huang, Dongfeng Gu   +11 more
wiley   +1 more source

Salvage Trans‐Sylvian Peri‐Insular Hemispherotomy After Embolic Hemispherectomy

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Hemispherectomy and hemispherotomy represent well‐established treatments for drug‐resistant hemispheric epilepsy. An alternative endovascular procedure has been explored for cases with challenging surgical anatomy, which seeks to achieve the clinical effect of hemispherectomy via embolization of the major cerebral arteries and ...
Michael E. Baumgartner, Sudha Kessler, Kathleen Galligan, James E. Baumgartner, Benjamin C. Kennedy   +4 more
wiley   +1 more source

Safety, Tolerability, and Pharmacokinetics of Donanemab in Healthy Chinese Participants: A Phase 1, Randomized, Double‐Blind, Placebo‐Controlled Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Alzheimer's disease (AD), characterized by β‐amyloid (Aβ) plaques and neurofibrillary tangles, is the leading cause of dementia globally. Donanemab is a humanized immunoglobulin G1 in development as a treatment to slow AD progression. This study aimed to evaluate the safety, tolerability, pharmacokinetics (PKs), and immunogenicity of donanemab
Junyu Xu, Nan Zhao, Yihui Wang, Ivelina Gueorguieva, Chenxi Qian, Yimin Cui   +5 more
wiley   +1 more source

Effects of Dimenhydrinate on Motor Behavior and Vascular Function: Possible Implications for the Field of Sports

Drug Testing and Analysis, EarlyView.
Regarding cardiovascular effects, DMH decreased vascular reactivity to phenylephrine and acetylcholine. We observed that the combination of DPH and 8‐Cl‐T was identified as the responsible for increasing blood pressure and heart rate in the biological model used.
Jazmín Flores‐Monroy, Diana Ramírez‐Hernández, Diego Lezama‐Martínez, Benjamín Velasco‐Bejarano   +3 more
wiley   +1 more source

Squamate ventricular cardiomyocytes: Ploidy, proliferation, and heart muscle cell size in the leopard gecko (Eublepharis macularius)

Developmental Dynamics, EarlyView.
Abstract Background While heart function is broadly conserved across vertebrates, the cellular phenotype of muscle cells (cardiomyocytes) varies across taxa and throughout ontogeny. Emerging evidence suggests that some attributes may correlate with the capacity for spontaneous cardiomyocyte replacement following injury.
Kathy Jacyniak, Karemna Barrera Jaimes, Minh Hanh Doan, Jordyn M. Chartrand, Matthew K. Vickaryous   +4 more
wiley   +1 more source

Pre‐oviposition development of the brown anole (Anolis sagrei)

Developmental Dynamics, EarlyView.
Abstract Background The brown anole, Anolis sagrei, has emerged as a representative squamate species for developmental studies during the past decades. Novel functional tools have been established to manipulate embryogenesis through genome editing or the introduction of small molecule inhibitors, and their effective use requires a thorough ...
Antonia Weberling, Natalia A. Shylo, Bonnie K. Kircher, Hannah Wilson, Melainia McClain, Marta Marchini, Katherine B. Starr, Thomas J. Sanger, Florian Hollfelder, Paul A. Trainor   +9 more
wiley   +1 more source