Results 141 to 150 of about 242,261 (346)

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

Advanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao, Xiaoli Cui, Huizhu Du, Zhuoqun Wang, Chang Liu, Linxin Zhang, Jianing Qi, Di Yang, Hui Yu, Shuang Yan, Wei Liu, Haiming Sun, Mengyang Wang   +12 more
wiley   +1 more source

Incidentally diagnosed Takayasu arteritis on thyroid ultrasonography showing prominent collateral vessels of thyroidal arteries and common carotid artery occlusion [PDF]

, 2014
Se Jin Nam, Eun‐Kyung Kim
openalex   +1 more source

Customizing Tactile Sensors via Machine Learning‐Driven Inverse Design

Advanced Science, EarlyView.
ABSTRACT Replicating the sophisticated sense of touch in artificial systems requires tactile sensors with precisely tailored properties. However, manually navigating the complex microstructure‐property relationship results in inefficient and suboptimal designs.
Baocheng Wang, Depeng Kong, Zhiao He, Jikai Liang, Yuyao Lu, Zikang Deng, Honghe Li, Mengke Wang, M. Jamal Deen, Zhiqiu Ye, Shuyao Zhou, Huayong Yang, Honghao Lyu, Jun Chen, Kaichen Xu, Geng Yang   +15 more
wiley   +1 more source

Using MSCT to Diagnose and Categorize High Bifurcation of the Common Carotid Artery Before Carotid Endarterectomy in Older Individuals

Российский журнал гериатрической медицины
Carotid endarterectomy (CEA) is the mainstay of treatment for carotid artery stenosis for the prevention of ischemic strokes. The variant anatomy of the structure of the brachiocephalic arteries, namely the high bifurcation of the common carotid artery ...
E. A. Kruglov, M. R. Hokonov
doaj   +1 more source

Cholesterol Promotes Lung Adenocarcinoma Brain Metastasis by Stabilizing EGFR Protein to Drive EMT, Metabolic Reprogramming, and Premetastatic Niche Formation

Advanced Science, EarlyView.
Cholesterol is revealed as a multitasking fuel for lung adenocarcinoma brain metastasis: it locks EGFR at the membrane to sustain AKT/NF‐κB–driven glycolysis and EMT, loosens the blood–brain barrier by promoting Claudin‐5 loss, and rewires microglia through IL‐4R lipid‐raft–JAK1/STAT6 signaling.
Ying Chen, Xiaoteng Cui, Xinyi Shi, Xu Yang, Yujing Cao, Haolin LI, Qi Zhan, Qixue Wang, Ang Li, Qihong Cheng, Yunfei Wang, Junhu Zhou, MingJie Wang, Chunsheng Kang, Xiaomin Liu   +14 more
wiley   +1 more source

Chlamydia pneumoniae in atherosclerotic middle cerebral artery [PDF]

, 2001
Background and Purpose—Atherosclerotic middle cerebral arteries are frequent sites of thrombosis, leading to stroke. Previous studies have suggested a role for Chlamydia pneumoniae in the pathogenesis of atherosclerosis.
Burián, Katalin, Gönczöl, Éva, Intzédy, László, Iványi, Béla, Karai, László, Kis, Zoltán, Szabó, Árpád, Virók, Dezső   +7 more
core  

Protected Carotid Artery Stenting Versus Endarterectomy in High-Risk Patients Reflections From SAPPHIRE [PDF]

, 2005
Dominique Thomas
openalex   +1 more source

Fate of External Carotid Artery Following Carotid Artery Stenting for Internal Carotid Artery near Occlusion

Biomedicines
Background: The external carotid artery (ECA) plays a vital role in facial perfusion and acts as a collateral pathway for cerebral blood flow during internal carotid artery (ICA) stenosis. In cases of carotid near-occlusion (CNO), characterized by severe ICA stenosis with hemodynamic changes, carotid artery stenting (CAS) is rising as a potential new ...
Dorota Łyko-Morawska, Michał Serafin, Julia Szostek, Magdalena Mąka, Iga Kania, Wacław Kuczmik   +5 more
openaire   +4 more sources

Effect Differences of Omega‐3 Fatty Acids From Plant Oil and Fish Oil on Human Health

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Omega‐3 fatty acids in plant oil is no less than fish oil on human health. ALA in plant oil takes directly healthy effects without conversion to DHA and EPA. Plant oil can be substitutes for fish oil to support partial ω‐3 fatty acids. For people who cannot afford fish oil, plant oil is also good for public health.
Mengxue Fang, Chunyan Xiang, Liangxiao Zhang, Peiwu Li   +3 more
wiley   +1 more source

Anterolaterally Projecting Clinoid Segment Aneurysm Causing Oculomotor Palsy, with an Anatomical Review of the Clinoid Segment of the Internal Carotid Artery

, 2021
Takato Tajiri, Kenji Fukuda, Toshiro Katsuta, Hiroshi Abe, Tooru Inoue   +4 more
openalex   +2 more sources