Results 111 to 120 of about 447,928 (350)

Carbon Monoxide Nanomodulator Reverses Ischemia‐Reperfusion Injury in Stroke: A Novel Dual‐Channel Therapy Mode of Co‐driving Neuroprotection and Neurogenesis

open access: yesAdvanced Science, EarlyView.
This work develops a biomimetic and reactive oxygen species‐activated carbon monoxide (CO) nanogenerator to penetrate blood‐brain barrier, arrive in stroke‐affected regions, and release CO in a controlled manner for an innovative dual‐channel therapy strategy via co‐driving neuroprotection and neurogenesis.
Xuegang Niu   +17 more
wiley   +1 more source

Introduction. Carotid endarterectomy versus carotid stenting. A never-ending story [PDF]

open access: yes, 2018
L'articolo discute le controversie relative all'accettazione in pratica clinica dello stentig ...
de Donato, Gianmarco   +2 more
core   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

open access: yesAdvanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li   +8 more
wiley   +1 more source

Assessment of hemodynamic parameters distribution in normal carotid artery by using computational fluid dynamics based on CE-MRA data

open access: yesBioscience Journal, 2018
This study was to analyze the in vivo distribution of wall shear stress (WSS), velocity and in-plane pressure difference in normal carotid artery by using computational fluid dynamics (CFD) based on contrast-enhanced MRA (CE-MRA) data and to determine ...
Xiao Li   +8 more
doaj   +3 more sources

Ultrasound IMT measurement on a multi-ethnic and multi-institutional database: Our review and experience using four fully automated and one semi-automated methods [PDF]

open access: yes, 2012
Automated and high performance carotid intima-media thickness (IMT) measurement is gaining increasing importance in clinical practice to assess the cardiovascular risk of patients. In this paper, we compare four fully automated IMT measurement techniques
Andrew Nicolaides   +10 more
core   +1 more source

Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury

open access: yesAdvanced Science, EarlyView.
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang   +11 more
wiley   +1 more source

Dissection of the Common Carotid Artery [PDF]

open access: yesJournal of Diagnostic Medical Sonography, 2000
Dissection of the aorta is a common catastrophic event affecting the aorta. However, aortic dissections do not normally extend into the common carotid arteries. This case study discusses such an occurrence and the role of sonography in its detection and diagnosis.
openaire   +1 more source

Targeted 2‐Deoxy‐D‐Ribose Delivery by Biomimetic Nanoplatform Activates EGFR for Accelerated Heart Valve Endothelialization

open access: yesAdvanced Science, EarlyView.
This study develops a biomimetic nanoplatform using erythrocyte membrane‐camouflaged, CD144 antibody‐functionalized nanoparticles to deliver 2‐deoxy‐D‐ribose (2dDR). This system promotes heart valve endothelialization by enhancing endothelial cell migration and proliferation via EGFR activation, while improving hemocompatibility.
Xiang Qiu   +11 more
wiley   +1 more source

The role of biomechanics in the assessment of carotid atherosclerosis severity: a numerical approach [PDF]

open access: yes, 2018
Numerical fluid biomechanics has been proved to be an efficient tool for understanding vascular diseases including atherosclerosis. There are many evidences that atherosclerosis plaque formation and rupture are associated with blood flow ...
Bou-said, Benyebka   +4 more
core  

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

open access: yesAdvanced Science, EarlyView.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li   +17 more
wiley   +1 more source

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