Results 91 to 100 of about 768,176 (386)

The association of the circle of Willis anomaly and risk of stroke in patients with carotid artery disease

Arquivos de Neuro-Psiquiatria
The circle of Willis is an important collateral system that maintains perfusion to the stenotic area from the contralateral carotid and basilar artery to the region of reduced brain perfusion.
Eylem Özaydın Göksu, Pınar Koç, Elif Küçükseymen, Ali Ünal, Fatma Genç, Elif Sarıönder Gencer, Aylin Yaman   +6 more
doaj   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Carotid artery disease in patients undergoing elective coronary artery bypass surgery [PDF]

, 2009
OBJECTIVE: To determine frequency of carotid artery disease in patients undergoing elective coronary artery bypass grafting (CABG) using Doppler sonography.STUDY DESIGN: Observational study. PLACE AND DURATION OF STUDY: Radiology Department, The Aga Khan
Ahmad, Nadeem, Akhtar, Waseem, Ali, Arif, Aslam, Mubashir, Sabih, Ayan   +4 more
core   +1 more source

Volumetric analysis of carotid plaque components and cerebral microbleeds: a correlative study [PDF]

, 2017
PURPOSE: The purpose of this work was to explore the association between carotid plaque volume (total and the subcomponents) and cerebral microbleeds (CMBs).
Anzidei, Michele, DI MARTINO, Michele, Francone, Marco, Lucatelli, Pierleone, Montisci, Roberto, Porcu, Michele, Saba, Luca, Sanfilippo, Roberto, Suri, Jasjit S.   +8 more
core   +1 more source

Risk Factors of Impaired Perfusion in Patients With Symptomatic Internal Carotid Artery Steno-Occlusive Disease [PDF]

, 2022
Xinxin Qiao, Jinfeng Duan, Nan Zhang, Yang Duan, Xinrui Wang, Yusong Pei, Zhihua Xu, Benqiang Yang, Miao Qi, Jinze Li   +9 more
openalex   +1 more source

Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury

Advanced Science, EarlyView.
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang, Xiuzhen Huang, Jialing Mou, Enci Wang, Yan Li, Wenjuan Pu, Yao Xie, Xiaoling Guo, Lixin Wang, Maoping Chu, Bin Zhou, Chao Niu   +11 more
wiley   +1 more source

Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis. [PDF]

, 2014
BackgroundIndividuals with rheumatoid arthritis (RA) are at increased risk for cardiovascular disease, partly due to systemic inflammation and endothelial dysfunction.
Del Puerto, Gus, Ganz, Peter, Graf, Jonathan, Grunfeld, Carl, Hsue, Priscilla Y, Imboden, John, Nitta, Elaine, Scherzer, Rebecca, Schnell Heringer, Amanda, Shigenaga, Judy, Wu, Yuaner   +10 more
core   +2 more sources

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

MECHANISMS OF DISEASE Acute Oxygen-Sensing Mechanisms [PDF]

, 2005
JOSEPH PRIESTLEY, ONE OF THE THREE SCIENTISTS CREDITED WITH THE discovery of oxygen, described the death of mice that were deprived of oxygen. However, he was also well aware of the toxicity of too much oxygen, stating, “For as a candle burns much faster
Buckler, Keith J., E. Kenneth Weir, M.D., López Barneo, José, Stephen L. Archer, M.D   +3 more
core  

Carotid Artery Sonography Findings in 291 Patients Undergoing Cabg

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2006
Introduction: Doppler ultrasonography (DUS) is the most preferable method for screening of carotid artery disease in patients undergoing CABG. The purpose of this study was to investigate the frequency of carotid artery disease and determine the relation
HR Dehghan, J Mirhosseini, Sh Baradaran, S Zare, MH Abdollahi, R Nafisi-Moghadam, Kh Forouzan-nia   +6 more
doaj