Results 71 to 80 of about 5,333,057 (253)

Waiting times for carotid endarterectomy in UK: observational study. [PDF]

, 2009
OBJECTIVES: To assess timeliness of carotid endarterectomy services in the United Kingdom. DESIGN: Observational study with follow-up to March 2008. SETTING: UK hospitals performing carotid endarterectomy.
Halliday, A, Rothwell, P, Clinical Effectiveness and Evaluation Unit, Royal College of Phy, Rudd, T, Hoffman, A, Rothwell, Peter M, Lees, T, Grant, Robert, Potter, John F, Halliday, AW, Kamugasha, Dora, Potter, JF, Horrocks, M, Halliday, Alison W, Hoffman, Alex, Halliday, Alison W., Horrocks, Michael, Grant, R, Rothwell, Peter M., Kamugasha, D, Rothwell, PM, Potter, John F., Lees, Tim, Naylor, R, Rudd, AG, Carotid Endarterectomy Steering Group, Vascular Society of Great Britain and Ireland, Rudd, Anthony G, Rudd, Anthony G., Naylor, Ross   +29 more
core   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Associations between blood glucose and carotid intima-media thickness disappear after adjustment for shared risk factors: the KORA F4 study. [PDF]

, 2012
The association between blood glucose and carotid intima-media thickness (CIMT) is considered to be established knowledge. We aimed to assess whether associations between different measures of glycaemia and CIMT are actually independent of anthropometric
Nina Ebert (107973), Jochen Seissler (107978), Kowall, B., Thiery, Joachim, Bernd Kowall, Kowall, Bernd, Christa Meisinger (39940), Thiery, J., Rathmann, W., Christa Meisinger, Seissler, J., Koenig, W., Wolfgang Rathmann, Then, C., Ebert, Nina, Wolfgang Koenig (26222), Meisinger, C., Cornelia Then, Cornelia Then (81529), Ebert, N., Wolfgang Rathmann (107976), Then, Cornelia, Koenig, Wolfgang, Joachim Thiery, Joachim Thiery (66414), Rathmann, Wolfgang, Meisinger, Christa, Wolfgang Koenig, Jochen Seissler, Bernd Kowall (107969), Nina Ebert, Seissler, Jochen   +31 more
core   +2 more sources

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

The safety and performance of the new Nitinol stent in the treatment of carotid artery stenosis : one and six month follow-up [PDF]

, 2009
Background The purpose of the trial was to evaluate the safety and performance of the new Protégé stent in the treatment of common and/or internal carotid artery stenoses. Methods The Protégé® GPS stent is a self-expanding Nitinol stent system.
Franke, Jennifer
core  

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

The association of the circle of Willis anomaly and risk of stroke in patients with carotid artery disease

Arquivos de Neuro-Psiquiatria
The circle of Willis is an important collateral system that maintains perfusion to the stenotic area from the contralateral carotid and basilar artery to the region of reduced brain perfusion.
Eylem Özaydın Göksu, Pınar Koç, Elif Küçükseymen, Ali Ünal, Fatma Genç, Elif Sarıönder Gencer, Aylin Yaman   +6 more
doaj   +1 more source

Carotid reconstruction under specific clinical conditions: unilateral carotid stenosis, contralateral carotid occlusion, bilateral carotid stenosis, and concomitant coronary artery disease

, 2023
Stroke has an immense burden on public health not only due to its high mortality but also because many of the survivors are left with a lifelong disability decreasing their quality of life.
Mathews, Robin Roy
core  

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Cardiovascular regulation and vascular structure in prehypertension and coronary heart disease [PDF]

, 2009
The aim of this thesis was to characterize vascular structure and different aspects of cardiovascular regulation in otherwise healthy subjects with slightly elevated blood pressure and compare to healthy subjects with normotension and also investigate ...
Myredal, Anna
core   +1 more source