Results 81 to 90 of about 636,322 (300)

Photo‐Biomodulation of the Hippocampus Using Near‐Infrared Laser to Enhance Cognitive Function in Mice

Advanced Science, EarlyView.
Here a transcranial photo‐biomodulation approach is developed using near‐infrared (NIR) laser on hippocampus of mice, revealing significant improvements in learning and memory ability of mice under normal and disease conditions. The improvement results from the high‐density cell‐induced NIR local energy deposition, neuronal activation, and axonogenesis
Wei‐Tong Pan, Han‐Wen Gu, Yan‐Bo Zhou, Sophie Ma, Daqing Ma, Pan‐Miao Liu, Jian‐Jun Yang   +6 more
wiley   +1 more source

Wogonin Attenuates Atherosclerosis via KLF11‐Mediated Suppression of PPARα‐YAP1‐Driven Glycolysis and Enhancement of ABCA1/G1‐Mediated Cholesterol Efflux

Advanced Science, EarlyView.
PPARα promotes KLF11 expression and recruits KLF11 and YAP1 to form a transcription complex, where KLF11 acts as a brake in PPARα‐YAP1‐mediated glycolysis. Wogonin reshapes the metabolism of macrophages from glycolysis to fatty acid oxidation via activation of the PPARα‐KLF11‐YAP1 pathway, by which wogonin reduces inflammation and foam cell formation ...
Chuanrui Ma, Yunqing Hua, Shu Yang, Yun Zhao, Wei Zhang, Yaodong Miao, Jing Zhang, Boxuan Feng, Guobin Zheng, Lan Li, Zhihao Liu, Han Zhang, Mingjun Zhu, Xiumei Gao, Guanwei Fan   +14 more
wiley   +1 more source

Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis

Advanced Science, EarlyView.
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li, Qi Xiang, Yan Zhang, Fuxue Luo, Yunfang Wu, Haitao Ran, Yang Cao   +6 more
wiley   +1 more source

Physical Activity and Characteristics of the Carotid Artery Wall in High‐Risk Patients—The SMART (Second Manifestations of Arterial Disease) Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundPhysical activity reduces the risk of vascular disease. This benefit is not entirely explained through an effect on vascular risk factors.
H. Myrthe Boss, Yolanda van der Graaf, Frank L. J. Visseren, Renske M. Van den Berg‐Vos, Michiel L. Bots, Gert Jan de Borst, Maarten J. Cramer, L. Jaap Kappelle, Mirjam I. Geerlings   +8 more
doaj   +1 more source

A promising marker for carotid artery disease: Monocyte to high-density lipoprotein ratio (MHR)

Sakarya Tıp Dergisi, 2020
Objectives: The aim of our study was to evaluate the relation between monocyte/high-density lipoprotein(HDL) ratio value and carotid artery stenosis in patients who underwent carotid angiography.Methods: To our study, 94 participants were enrolled (68 ...
Mehmet Kirişçi
doaj   +1 more source

Macrophage WEE1 Directly Binds to and Phosphorylates NF‐κB p65 Subunit to Induce Inflammatory Response and Drive Atherosclerosis

Advanced Science, EarlyView.
The present study shows that macrophage WEE1 drives NF‐κB activation and inflammatory atherosclerosis by directly phosphorylating p65 at S536. This finding illustrates a macrophage‐specific WEE1‐p65 axis in regulating inflammatory atherosclerosis and points out new directions to broaden the clinical applications for WEE1 inhibitors in atherosclerosis ...
Zhuqi Huang, Sirui Shen, Weixin Li, Mengyang Wang, Yudie Yang, Wu Luo, Xue Han, Zheng Xu, Julian Min, Xiaohong Long, Weijian Huang, Gaojun Wu, Yi Wang, Guang Liang   +13 more
wiley   +1 more source

Ferrocene‐Functionalized Black Phosphorus Nanoplatform Enables Targeted and Prolonged MRI Visualization of Atherosclerotic Plaques

Advanced Science, EarlyView.
Aminoferrocene is employed to modify black phosphorus, generating stable phosphorus radicals (FcP). The FcP is then functionalized with hyaluronic acid (HA) to produce the HA‐FcP radical complex, thereby developing a novel, highly efficient, sensitive, long‐lasting, and low‐heavy‐metal‐content radical contrast agent for targeted imaging of ...
Xiao Huang, Yuanyuan Zhao, Miao Zhou, Yukang Guo, Haiyun Wang, Yuanyuan Chen, Jian Peng   +6 more
wiley   +1 more source

Mesenteric thrombosis: An unusual complication of severe acute pancreatitis—Report of two cases

Advances in Digestive Medicine, EarlyView.
Abstract The incidence of acute pancreatitis is 34 per 100 000 people in the general population and is on the rise. Approximately 15% to 20% of all patients experience severe pancreatitis, with a mortality rate nearing 20%. This condition is often linked to vascular complications, although mesenteric thrombosis is a rare presentation.
Asya Zubillaga‐Mares, Erika Barlandas‐Quintana, Aranza Judith Sánchez‐Lopez, Minnet Serrano‐Sanchez, Javier Meza‐Hernandez, Alejandra Nuñez‐Venzor   +5 more
wiley   +1 more source

What is the current status of invasive treatment of extracranial carotid artery disease?

Stroke, 2011
Year 2011 sees the publication of U.S. guidelines that recommend expanding indications for carotid artery stenting into "average-risk" patients, whereas guidelines from Australia/New Zealand largely do not.
G. Lanzino, M. Tymianski, A. Naylor, R. Naylor   +3 more
semanticscholar   +1 more source

Adverse Cardiovascular Risk Profile and Increased Diurnal Salivary Cortisol in Girls With Turner Syndrome: An Exploratory Study

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Patients with Turner Syndrome (TS) and those exposed to high concentrations of glucocorticoids have a number of characteristics in common, including an increased risk of cardiovascular disease. Pediatric TS patients underwent studies of salivary cortisol (SC) and cortisone (SCn), body composition, continuous glucose monitoring, vascular ...
Lily Jones, Julie Park, Silothabo Dliso, Daniel B. Hawcutt, Alena Shantsila, Gregory Y. H. Lip, Joanne Blair   +6 more
wiley   +1 more source