Results 101 to 110 of about 179,773 (311)

Targeted 2‐Deoxy‐D‐Ribose Delivery by Biomimetic Nanoplatform Activates EGFR for Accelerated Heart Valve Endothelialization

Advanced Science, EarlyView.
This study develops a biomimetic nanoplatform using erythrocyte membrane‐camouflaged, CD144 antibody‐functionalized nanoparticles to deliver 2‐deoxy‐D‐ribose (2dDR). This system promotes heart valve endothelialization by enhancing endothelial cell migration and proliferation via EGFR activation, while improving hemocompatibility.
Xiang Qiu, Gaofeng Li, Wenyi Wan, Jinsheng Li, Ge Yan, Shijie Wang, Xiuqi Hu, Zongqi Han, Yazheng Shan, Ying Zhou, Nianguo Dong, Weihua Qiao   +11 more
wiley   +1 more source

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

Advanced Science, EarlyView.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li, Yong‐Dong Guo, Xiao‐Wen Zhang, Zhi‐Yong Du, Yu‐Qi Wang, Zhuo Yang, Qian‐Wei Luo, Fang‐Fang Zhuo, Tian‐Tian Wei, Zheng‐Ping Liu, Bo Han, Wei Yu, Pei‐Pei Zhang, Wei Zhou, Zhi‐Yuan Lu, Peng‐Fei Tu, Chun‐Hong Zheng, Ke‐Wu Zeng   +17 more
wiley   +1 more source

Blood flow analysis in carotid artery bifurcation by two-dimensional ultrasonic-measurement-integrated simulation

Journal of Biomechanical Science and Engineering, 2014
If highly precise elucidation of the blood flow characteristics in a carotid bifurcation was possible, it would be widely applicable to diagnosis of circulatory diseases such as arteriosclerosis and cerebrovascular disease.
Hiroko KADOWAKI, Toshiyuki HAYASE, Kenichi FUNAMOTO, Shusaku SONE, Tadashi SHIMAZAKI, Takao JIBIKI, Koji MIYAMA   +6 more
doaj   +1 more source

Transient Ischemic Attack in the Setting of Carotid Atheromatous Disease with a Persistent Primitive Hypoglossal Artery Successfully Treated with Stenting: A Case Report [PDF]

, 2016
Meng Huang, Marc Moisi, Michael Zwillman, John Volpi, Orlando Díaz, Richard Klucznik   +5 more
openalex   +1 more source

A Metalloporphyrin Nanosystem Enables Non‐Invasive Visualization and Specific Treatment for Thrombosis and Ischemic Stroke

Advanced Science, EarlyView.
Thrombotic ischemic stroke is a severe neurological disease of the brain that presents major challenges for effective diagnosis and treatment. Precisely engineered Ir and Mn cores within a single porphyrin framework of 4IrMn nanoparticles enable endogenous ONOO−‐ or laser‐activated switching among NIR‐CL imaging, photothermal / photodynamic therapy ...
Ziwei Wang, Liping Zhang, Zihan Wu, Nan Xiao, Wenxin Zheng, Yachao Wang, Gelin Xu, Dongxia Zhu, Martin R. Bryce, Lijie Ren, Ben Zhong Tang   +10 more
wiley   +1 more source

Systematic Preoperative Coronary Angiography and Stenting Improves Postoperative Results of Carotid Endarterectomy in Patients with Asymptomatic Coronary Artery Disease: A Randomised Controlled Trial [PDF]

, 2009
Giulio Illuminati, Jean‐Baptiste Ricco, Cesare Greco, Enrico Mangieri, F. Calio', Gianluca Ceccanei, Maria Antonietta Pacilè, Michele Schiariti, Gaetano Tanzilli, Francesco Barillà, Vincenzo Paravati, Giuseppe Mazzesi, Fabio Miraldi, Luigi Tritapepe   +13 more
openalex   +1 more source

Atherosclerotic Carotid Artery Disease

, 2022
Ibrahim Al Kindi, Sara Al Adawi, Edwin Stephen, Saleh Ba Awain, Arunodaya R. Gujjar, Ibrahim Abdelhedy, Hanan Al Mawaali, Khalifa Al-Wahaibi   +7 more
openalex   +2 more sources

Monocyte‐Differentiation‐Activated Fluorescent “Scout” Probe for Precise in Vivo Detection of Vulnerable Plaque

Advanced Science, EarlyView.
An innovative monocyte‐differentiation‐activated fluorescent “scout” probe (MDAF) leverages the inherent chemotaxis of monocytes toward vulnerable plaques (VAP) to enable efficient targeted delivery while achieving spatiotemporally controllable activation of its AIE fluorescent signals with the dynamic differentiation of monocytes, providing an ...
Zechuan Li, Jiankai Dong, Zhengkun Liu, Chaoke Zhang, Jisen Li, Ying Tao, Ding Yang, Yansong Liu, Haoting Chen, Lu Liu, Jingsen Ji, Feng Cao, Dan Ding, Qian Liu, Chenxing Fu, Weisheng Guo   +15 more
wiley   +1 more source

Improving Computer-Aided Medical Diagnosis Using Generative Adversarial Networks for Carotid Artery Ultrasound Image Data Augmentation and Classification

Journal of Electrical Engineering and Computer
Cardiovascular diseases are a leading cause of death globally, making early detection of atherosclerosis critical for prevention. Carotid artery ultrasound imaging is a common diagnostic tool; however, the limited availability of labelled medical images ...
Ricardo Fitas, João Gonçalves
doaj   +1 more source

Carotid artery ultrasound for evaluating the degree of stenosis and plaque composition in patients with coronary heart disease [PDF]

, 2019
Ye Zhu, Jia You, Chao Xu, Xiang Gu
openalex   +1 more source