Results 101 to 110 of about 116,719 (299)

Advances in endovascular therapy for ischemic cerebrovascular diseases

Chronic Diseases and Translational Medicine, 2016
Endovascular therapy for ischemic cerebrovascular diseases has developed rapidly in recent years. The latest clinical trials of acute ischemic stroke have shown promising results with the continued advancement of concepts, techniques, and materials ...
Jun Lu, Daming Wang
doaj   +1 more source

Clinical Outcomes and Patient Experiences With Celiprolol Therapy in Vascular Ehlers–Danlos Syndrome: The First Non‐European Cohort

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Vascular Ehlers–Danlos syndrome (vEDS) is a hereditary connective tissue disorder caused by heterozygous pathogenic variants in COL3A1. European studies have shown that celiprolol may reduce the risk of life‐threatening vascular events, but outcomes in non‐European populations and the therapy's psychological impact remain unclear. We conducted
Megumi Furuhata‐Yoshimura, Tomomi Yamaguchi, Tomoki Kosho   +2 more
wiley   +1 more source

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim, Anat Abramovich, Sara Via‐Dorembus, Gali Heimer, Bruria Ben‐Zeev, Etai Adam, Assaf A. Barg, Jonathan Roth, Basheer Sheick‐Yousif, Rony Beeri Berkowiz, Michal Feldon, Haim Bassan, Moran Hausman‐Kedem   +12 more
wiley   +1 more source

Cardiovascular regulation and vascular structure in prehypertension and coronary heart disease

, 2009
The aim of this thesis was to characterize vascular structure and different aspects of cardiovascular regulation in otherwise healthy subjects with slightly elevated blood pressure and compare to healthy subjects with normotension and also investigate ...
Myredal, Anna
core  

Epidemiology and Pathology of Carotid Artery Diseases

Carotid artery atherosclerosis is a common vascular disorder characterised by plaque deposition within the carotid arteries, major arteries supplying blood to the brain.
Lindholt, Jes S.; id_orcid
core   +1 more source

Mechanistic investigation of Liujing Toutong tablet in the treatment of cerebral ischemia–reperfusion injury in rats by the integration of serum pharmacochemistry and metabolomics

Animal Models and Experimental Medicine, EarlyView.
The research strategy for pharmacodynamics, serum pharmacochemistry, metabolomics, and network pharmacology analysis method in intervention effects of LTT are illustrated. Abstract Background Liujing Toutong tablet (LTT) is a traditional Chinese patent medicine.
Zihan Yu, Ke Pei, Xiulin Wang, Wenling Li, Hongchang Li, Wangyang Xie, Xianglong Meng, Tingting Zhao, Yan Ning, Haixin Liu, Wenbin He   +10 more
wiley   +1 more source

Chrysin alleviates pressure overload–induced myocardial remodeling through regulating the PI3K/AKT/NRF2 pathway–mediated oxidative stress response

Animal Models and Experimental Medicine, EarlyView.
In this study, we primarily simulated pathological myocardial remodeling induced by transverse aortic constriction surgery and found significant cardiac hypertrophy and fibrosis, characterized by deteriorated cardiac function. Oxidative stress response is considered as a pivotal pathological process, which contributes to inflammation and apoptosis of ...
Yijia Wang, Xing Feng, Shuhui Zhao, Yuchong Fu, Ao Zhang, Xiaofeng Shen, Bowen Yu, Yihao Wang, Jiahui Lin, Bing Zhang, Weiping Ji, Lianpin Wu, Xiaoling Guo   +12 more
wiley   +1 more source

Improving Computer-Aided Medical Diagnosis Using Generative Adversarial Networks for Carotid Artery Ultrasound Image Data Augmentation and Classification

Journal of Electrical Engineering and Computer
Cardiovascular diseases are a leading cause of death globally, making early detection of atherosclerosis critical for prevention. Carotid artery ultrasound imaging is a common diagnostic tool; however, the limited availability of labelled medical images ...
Ricardo Fitas, João Gonçalves
doaj   +1 more source

Blood flow analysis in carotid artery bifurcation by two-dimensional ultrasonic-measurement-integrated simulation

Journal of Biomechanical Science and Engineering, 2014
If highly precise elucidation of the blood flow characteristics in a carotid bifurcation was possible, it would be widely applicable to diagnosis of circulatory diseases such as arteriosclerosis and cerebrovascular disease.
Hiroko KADOWAKI, Toshiyuki HAYASE, Kenichi FUNAMOTO, Shusaku SONE, Tadashi SHIMAZAKI, Takao JIBIKI, Koji MIYAMA   +6 more
doaj   +1 more source

An investigation into stent expansion using numerical and experimental techniques [PDF]

, 2009
Extensive finite element analyses have been carried out by researchers to investigate the difference in the mechanical loading induced in vessels stented with various different stent designs and the influence of this loading on restenosis outcome.
Toner, Deborah
core