α‐Synuclein Promotes Atherosclerosis by Impairing Macrophage Autophagic Flux
Extracellular α‐synuclein activates the FLOT1‐PI3K‐mTOR axis to block autophagosome‐lysosomal fusion and lipophagy, thereby promoting macrophage foaming and atherosclerosis. Knockdown of FLOT1 or inhibition of PI3K‐mTOR rescues these effects. The graphical abstract image was created with Figdraw.
Mengting Qin +8 more
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Multi-Omics and Machine Learning Integration Identifies Key Endothelial Modules in Carotid Artery Stenosis. [PDF]
Wu J +5 more
europepmc +1 more source
Mitochondrial fission‐fusion imbalance contributes to age‐related cardio‐cerebral diseases like Alzheimer's disease, Parkinson's disease, Cerebral Infarction, Arteriosclerosis, Myocardial Infarction, Cardiac valve disease, Hypertension, and Cardiomyopathy. This review summarizes its regulatory mechanisms and interventions.
Yuyao Yin, Zijian Li
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Relationship between Vascular Tortuosity Rate and Atherosclerotic Risk Factors in Patients with Carotid Artery Stenosis. [PDF]
Tsuji M +12 more
europepmc +1 more source
Abstract Objectives We aimed to determine the prevalence of metabolic disorders, liver steatosis and metabolic dysfunction‐associated steatotic liver disease (MASLD) in a cohort of middle‐aged women with HIV (WoWH) and to explore associations between liver steatosis, visceral fat depots and carotid atherosclerosis.
Mariacristina Poliseno +13 more
wiley +1 more source
Retropharyngeal Internal Carotid Artery Stenosis: A Case-Based Narrative Review. [PDF]
Caruso C +7 more
europepmc +1 more source
Radial Versus Femoral Access for Carotid Artery Stenting in Patients With Carotid Artery Stenosis: Protocol of the Multicenter RACE-CAS Randomized Trial. [PDF]
Liu R +12 more
europepmc +1 more source
A Treated Case of Internal Carotid Artery Stenosis Associated with an Occipital Artery Originating from the Internal Carotid Artery. [PDF]
Miyazaki Y, Hori S, Umesaki A, Masuo O.
europepmc +1 more source
Same lesion, different outcomes: hemodynamic correlates of ischemic stroke in unilateral high-grade internal carotid artery stenosis or occlusion - a retrospective transcranial Doppler study. [PDF]
Jia Y +8 more
europepmc +1 more source

