Results 141 to 150 of about 141,961 (310)

Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management

Clinical Endocrinology, EarlyView.
ABSTRACT Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21‐hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long‐term use of supraphysiological doses and multiple factors inherent to the disease itself have led
Jialin Mu, Yue Li, Meng Sun, Yulin Li, Panpan Li, Hui Zou   +5 more
wiley   +1 more source

Association between triglyceride-glucose index and subclinical carotid atherosclerosis in systemic lupus erythematosus: a cohort-based study

Frontiers in Immunology
ObjectiveTo investigate the association between triglyceride-glucose (TyG) index and carotid atherosclerosis in patients with systemic lupus erythematosus (SLE).MethodsIn this tertiary-center cross-sectional study, 333 consecutive SLE patients undergoing
Wenhui Xie, Minjie Li, Hong Huang, Yong Fan, Dai Gao, Jiaying Zhang, Zhuoli Zhang   +6 more
doaj   +1 more source

Transformative Advances in Vascular Surgery: Five Decades of Innovation in the Management of Aortic, Carotid, and Peripheral Arterial Disease

World Journal of Surgery, EarlyView.
Ghaleb A. Darwazeh, William Q. Duong, Ramola M. Panchal, Ahmed M. Abou‐Zamzam   +3 more
wiley   +1 more source

Prediabetes, Malignant Ventricular Hypertrophy and Stroke: The SPRINT Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Prediabetes and left ventricular hypertrophy (LVH) are common risk factors in adults with hypertension. Whether their coexistence, particularly in the presence of subclinical myocardial injury or stress (malignant LVH), confers a heightened stroke risk is unknown.
Arnaud D. Kaze, Stephen P. Juraschek, Jordana B. Cohen, Siddharth Singh, Chiadi E. Ndumele, Christie M. Ballantyne, Jarrett D. Berry, Justin B. Echouffo‐Tcheugui   +7 more
wiley   +1 more source

Comparison of PREDICTS atherosclerosis biomarker changes after initiation of new treatments in patients with SLE [PDF]

, 2019
Objective Patients with SLE have an increased risk ofatherosclerosis (ATH) that is not adequately explainedby traditional risk factors. We previously described thePredictors of Risk for Elevated Flares, Damage Progression,and Increased Cardiovascular ...
Chen, Weiling, Grossman, Jennifer, Hahn, Bevra, McMahon, Maureen, Sahakian, Lori, Skaggs, Brian, Wong, Weng Kee   +6 more
core  

Carotid artery atherosclerosis

European Heart Journal
Cardiovascular disease remains a prominent cause of disability and premature death worldwide. Within this spectrum, carotid artery atherosclerosis is a complex and multifaceted condition, and a prominent precursor of acute ischaemic stroke and other cardiovascular events.
Saba, Luca, Cau, Riccardo, Vergallo, Rocco, Kooi, M Eline, Staub, Daniel, Faa, Gavino, Congiu, Terenzio, Ntaios, George, Wasserman, Bruce A, Benson, John, Nardi, Valentina, Kawakami, Rika, Lanzino, Giuseppe, Virmani, Renu, Libby, Peter   +14 more
openaire   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

Cholesterol accumulation in monocytes is associated with the severity of diabetic complications and the efficacy of glycemic control interventions in patients with type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
This study reveals that monocyte cholesterol accumulation correlates with the severity of diabetic complications and predicts post‐discharge glycemic deterioration. These findings suggest that monocytic cholesterol serves as a novel translational biomarker reflecting ‘metabolic memory’ and therapeutic resistance in patients with type 2 diabetes ...
Hideyuki Okuma, Takahiro Tsutsumi, Asako Miyazaki, Kyoichiro Tsuchiya   +3 more
wiley   +1 more source

Pathophysiological link between carotid atherosclerosis and cerebral white matter lesions

Scientific Reports
Carotid atherosclerosis is associated with white matter hyperintensity (WMH), potentially resulting in cognitive and gait problems. We assessed the relationship between carotid atherosclerosis patterns and regional WMH, offering insights into possible ...
Wookjin Yang, Keun-Hwa Jung, Kyung-Il Park, Matthew Chung, Jiyeon Ha, Eung-Joon Lee, Han-Yeong Jeong, Jeong-Min Kim, Seung-Hoon Lee   +8 more
doaj   +1 more source

IgE And IgG Antibody Responses to α‐Gal and Association With Carotid Stenosis in Swedish Patients

Allergy, EarlyView.
Marija Perusko, Danijela Apostolovic, Jeanette Grundström, Malin Kronqvist, Mirjana Radomirovic, Anna Smed‐Sörensen, Ulf Hedin, Marianne van Hage   +7 more
wiley   +1 more source