Results 61 to 70 of about 123,796 (172)
Pulmonary hypertension is driven by dynamic crosstalk beyond the physical connection between the heart and lung, involving neurohormonal systems, immune pathways, and peripheral organs. This review highlights how multisystem signaling contributes to disease progression and may reveal new diagnostic and therapeutic targets.
Alejandro A. Vega +4 more
wiley +1 more source
Cancer Risk in Marfan Syndrome: A Swedish Population‐Based Cohort Study
The cancer risk in Marfan syndrome, an autosomal dominant connective tissue disorder, largely remains to be explored. In this population‐based matched cohort study of 1544 Swedish patients, the overall cancer risk in adults with Marfan syndrome showed no significant increase, except for the risk of endocrine tumours with a nearly threefold increase ...
Ida Nordgren +8 more
wiley +1 more source
Predictive haemodynamics in a one-dimensional human carotid artery bifurcation. Part II: application to graft design [PDF]
A Bayesian surrogate modelling technique is proposed that may be able to predict an optimal bypass graft configuration for patients suffering with stenosis in the internal carotid artery (ICA). At the outset, this statistical technique is considered as a
Kolachalama, V. B. +3 more
core +1 more source
The histological study of the carotid bodies of human cadavers was performed using light microscopy and hematoxylin and eosin staining technique. We found good criteria to distinguish the cell types of this structure.
Kunnika Chatyingmongkol +1 more
doaj
High‐altitude hypobaric hypoxia activates multiorgan GPCR signaling networks that regulate ventilatory responses, cerebral endothelial barrier integrity, erythropoiesis and red blood cell metabolism, pulmonary vascular remodeling, and cardiac adaptation. Dysregulated GPCR pathways contribute to acute and chronic high‐altitude diseases, while clinically
Qing Zhao +13 more
wiley +1 more source
Neurocardiology: Brain–Heart Interactions in the Heart
The heart and brain maintain systemic homeostasis through bidirectional communication involving neural, biochemical, and mechanical pathways. Dysregulation of these pathways contributes to a spectrum of conditions involving heart–brain interactions, including Takotsubo syndrome, the epileptic heart, stroke–heart syndrome, heart failure, cardiac ...
Wentao Wang +3 more
wiley +1 more source
Supra/ para condylar approach for resection of GLOMUS jugular tumor
Background: Glomus jugulare tumors are rare, highly vascular paragangliomas arising from the jugular bulb. Their intimate relationship with the lower cranial nerves, internal carotid artery, and sigmoid sinus makes complete resection technically ...
Razan Almufarriji, Mohammed Bafaquh
doaj +1 more source
Update on the Pathophysiology, Aetiology and Management of Central Sleep Apnoea
ABSTRACT Central sleep apnoea (CSA) of the periodic breathing type occurs during the transition between wakefulness and stage 1 and 2 non‐REM sleep. In adults at sea level, it occurs most commonly due to advanced heart failure (HF) or chronic opioid use and in ~5% of obstructive sleep apnoea patients initiating CPAP.
Sahan D. Chandrasekara +1 more
wiley +1 more source
Neurotransmission in the carotid body: transmitters and modulators between glomus cells and petrosal ganglion nerve terminals [PDF]
The carotid body (CB) is the main arterial chemoreceptor. The most accepted model of arterial chemoreception postulates that carotid body glomus (type 1) cells are the primary receptors, which are synaptically connected to the nerve terminals of petrosal
Alcayaga Urbina, Julio +1 more
core
Oxygen-sensing by ion channels and mitochondrial function in carotid body glomus cells [PDF]
Carotid body glomus cells release transmitters in response to hypoxia due to the increase of excitability resulting from inhibition of O2-regulated K+ channels. The mechanisms involved in the detection of changes of O2 tension are unknown.
Piruat Palomo, José Ignacio +3 more
core +1 more source

